Recent publications

  • Article in journal

    Rofo, Fadi; Yilmaz, Canan Ugur; Metzendorf, Nicole G.; Gustavsson, Tobias et al.

    Enhanced neprilysin-mediated degradation of hippocampal A beta 42 with a somatostatin peptide that enters the brain

    Part of Theranostics, p. 789-804, 2021.

    Open access
  • Doctoral thesis, comprehensive summary

    Eriksson, Johanna

    Drug absorption in the lungs: studies in the isolated perfused rat lung model combined with physiologically based biopharmaceutics modelling

    Open access
  • Article in journal

    Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

    Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

    Part of Methods in Molecular Biology, p. 171-180, 2021.

  • Article in journal

    Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

    Part of European Journal of Pharmacology, 2021.

  • Article in journal

    Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

    Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

    Part of Cellular & Molecular Biology Letters (Druk), 2021.

    Open access
  • Article in journal

    Frances-Soriano, Laura; Leino, Mattias; Dos Santos, Marcelina Cardoso; Kovacs, Daniel et al.

    In Situ Rolling Circle Amplification Förster Resonance Energy Transfer (RCA-FRET) for Washing-Free Real-Time Single-Protein Imaging

    Part of Analytical Chemistry, p. 1842-1850, 2021.

  • Article in journal

    Gandasi, Nikhil R.; Arapi, Vasiliki; Mickael, Michel E.; Belekar, Prajakta A. et al.

    Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle

    Part of International Journal of Molecular Sciences, 2021.

    Open access
  • Article in journal

    Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

    Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

    Part of Science Advances, 2021.

    Open access
  • Article in journal

    Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

    N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

    Part of Bioorganic & Medicinal Chemistry, 2021.

  • Article in journal

    Wieslander, Håkan; Harrison, Philip J.; Skogberg, Gabriel; Jackson, Sonya et al.

    Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images

    Part of IEEE journal of biomedical and health informatics, p. 371-380, 2021.

    Open access
  • Article in journal

    Ibrahim, Moustafa M. A.; Redestad, Erik; Kjellsson, Maria C

    Optimal Designs for Model-Based Assessment of Insulin Sensitivity and Glucose Effectiveness.

    Part of Journal of clinical pharmacology, p. 116-124, 2021.

  • Article in journal

    Sharan, Satish; Fang, Lanyan; Lukacova, Viera; Chen, Xiaomei et al.

    Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

    Part of CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, p. 220-228, 2021.

  • Article in journal

    Zelleroth, Sofia; Nylander, Erik; Örtenblad, Axel; Stam, Frida et al.

    Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures.

    Part of Journal of Steroid Biochemistry and Molecular Biology, 2021.

  • Article in journal

    Eltahir, mohmo394; Fletcher, E.; Dynesius, L.; Jarblad, J. L. et al.

    Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients

    Part of International Immunopharmacology, 2021.

    Open access
  • Article in journal

    Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Kyrre, Thalberg et al.

    On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

    Part of International Journal of Pharmaceutics, 2021.

    Open access
  • Article in journal

    Germovsek, Eva; Hansson, Anna; Karlsson, Mats O.; Westin, Ake et al.

    A Time-to-Event Model Relating Integrated Craving to Risk of Smoking Relapse Across Different Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 416-423, 2021.

    Open access
  • Article in journal

    Blamey, Ben; Toor, Salman; Dahlö, Martin; Wieslander, Håkan et al.

    Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit.

    Part of GigaScience, 2021.

    Open access
  • Article in journal

    Meier, Silvio R.; Sehlin, Dag; Hultqvist, Greta; Syvänen, Stina

    Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease

    Part of Molecular Imaging and Biology, 2021.

    Open access
  • Article in journal

    Lyauk, Yassine Kamal; Jonker, Daniel M.; Hooker, Andrew; Lund, Trine Meldgaard et al.

    Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

    Part of AAPS Journal, 2021.

    Open access
  • Doctoral thesis, comprehensive summary
    Room A1:107, BMC, Husargatan 3, Uppsala 2021-05-07 09:15

    Fridjonsdottir, Elva

    Imaging neurochemical changes associated with Parkinson´s disease and L-DOPA-induced dyskinesia using mass spectrometry

    Open access
  • Article in journal

    Ullah, Junaid; Hashmi, Satwat; Ali, Arslan; Khan, Faisal et al.

    Pericardial fluid proteomic label-free quantification of differentially expressed proteins in ischemic heart disease patients with systolic dysfunction by nano-LC-ESI-MS/MS analysis

    Part of RSC Advances, p. 320-327, 2021.

    Open access
  • Article in journal

    Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

    Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

    Part of American Journal of Clinical Nutrition, p. 110-121, 2020.

    Open access
  • Article in journal

    Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

    Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

    Part of Bioorganic chemistry (Print), 2020.

  • Article in journal

    Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Article in journal

    Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

    Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Article in journal

    Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Article in journal

    Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

    A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

    Part of Journal of Antimicrobial Chemotherapy, p. 400-408, 2020.

  • Article in journal

    Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

    The effect of food on the pharmacokinetics of oral ivermectin

    Part of Journal of Antimicrobial Chemotherapy, p. 438-440, 2020.

  • Article in journal

    Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

    Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Article in journal

    Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

    Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 238-245, 2020.

  • Article in journal

    Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Article in journal

    Oliw, Ernst H; Hamberg, Mats

    Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

    Part of Rapid Communications in Mass Spectrometry, 2020.

  • Article in journal

    Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

    Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

    Part of Journal of Antimicrobial Chemotherapy, p. 609-617, 2020.

    Open access
  • Article in journal

    Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

    Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

    Part of International Journal of Infectious Diseases, p. 133-140, 2020.

    Open access
  • Article in journal

    Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Part of Oncoimmunology, 2020.

    Open access
  • Article in journal

    Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

    Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Article in journal

    Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Part of ChemistryOpen, p. 325-337, 2020.

    Open access
  • Article in journal

    Thorsted, Anders; Tano, Eva; Kaivonen, Kia; Sjölin, Jan et al.

    Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime.

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Doctoral thesis, comprehensive summary

    Lundberg, Stina

    Adolescent behavior: Links to early-life stress and alcohol in male and female rats

    Open access
  • Article in journal

    Tanneau, Lénaïg; Karlsson, Mats; Svensson, Elin

    Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis

    Part of British Journal of Clinical Pharmacology, p. 913-922, 2020.

    Open access
  • Article in journal

    Centanni, Maddalena; Friberg, Lena

    Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Article in journal

    Arshad, Usman; Ploylearmsaeng, Su-arpa; Karlsson, Mats; Doroshyenko, Oxana et al.

    Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients

    Part of Cancer Chemotherapy and Pharmacology, p. 711-722, 2020.

    Open access
  • Article in journal

    Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Part of RSC Medicinal chemistry, p. 234-244, 2020.

  • Article in journal

    Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

    Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Article in journal

    Lundberg, Stina; Nylander, Ingrid; Roman, Erika

    Behavioral profiling in early adolescence and early adulthood of male Wistar rats after short and prolonged maternal separation

    Part of Frontiers in Behavioral Neuroscience, 2020.

    Open access
  • Article in journal

    Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

    Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

    Part of Molecular Pharmaceutics, p. 1458-1469, 2020.

  • Doctoral thesis, comprehensive summary

    Thorsted, Anders

    Pharmacometrics to characterize innate immune response and antibacterial treatments

    Open access
  • Article in journal

    Olsson, Anna; Wistrand-Yuen, Pikkei; Nielsen, Elisabet I.; Friberg, Lena et al.

    Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Article in journal

    Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Part of Acta Physiologica, 2020.

  • Article in journal

    Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

    Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

    Part of Frontiers in Chemistry, 2020.

    Open access