Recent publications

  • Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

    Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

    Part of Methods in Molecular Biology, p. 171-180, 2021.

  • Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

    Part of European Journal of Pharmacology, 2021.

  • Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

    N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

    Part of Bioorganic & Medicinal Chemistry, 2021.

  • Nylander, Erik; Zelleroth, Sofia; Nyberg, Fred; Gröndbladh, Alfhild et al.

    The effects of morphine, methadone, and fentanyl on mitochondria: A live cell imaging study

    Part of Brain Research Bulletin, p. 126-134, 2021.

  • Zelleroth, Sofia; Nylander, Erik; Örtenblad, Axel; Stam, Frida et al.

    Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures

    Part of Journal of Steroid Biochemistry and Molecular Biology, 2021.

    Open access
  • Nikulin, Sergey; Zakharova, Galina; Poloznikov, Andrey; Raigorodskaya, Maria et al.

    Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

    Part of Frontiers in Genetics, 2021.

    Open access
  • Lukoyanov, Nikolay; Watanabe, Hiroyuki; Carvalho, Liliana S.; Kononenko, Olga et al.

    Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

    Part of eLIFE, 2021.

    Open access
  • Carvalho, Liliana S.; Brito, Helena M.; Lukoyanova, Elena A.; Maia, Gisela H. et al.

    Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring

    Part of European Journal of Neuroscience, p. 3621-3633, 2021.

    Open access
  • Bakalkin, Georgy; Nosova, Olga; Sarkisyan, Daniil; Hallberg, Mathias et al.

    Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats

    Part of Experimental Brain Research, p. 2221-2232, 2021.

    Open access
  • Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Part of ChemistryOpen, p. 325-337, 2020.

    Open access
  • Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Part of RSC Medicinal chemistry, p. 234-244, 2020.

  • Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Part of Acta Physiologica, 2020.

  • Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

    Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

    Part of Biomolecules, 2020.

    Open access
  • Mpakali, Anastasia; Saridakis, Emmanuel; Giastas, Petros; Maben, Zachary et al.

    Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

    Part of ACS Medicinal Chemistry Letters, p. 1429-1434, 2020.

  • Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

    Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

    Part of Brain communications, 2020.

    Open access
  • Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

    Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

    Part of Journal of Neurotrauma, 2020.

  • Seyer, Benjamin; Diwakarla, Shanti; Burns, Peta; Hallberg, Anders et al.

    Insulin-regulated aminopeptidase inhibitor-mediated increases in dendritic spine density are facilitated by glucose uptake

    Part of Journal of Neurochemistry, p. 485-494, 2020.

    Open access
  • Watanabe, Hiroyuki; Nosova, Olga; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

    Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

    Part of Brain Communications, 2020.

    Open access
  • Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

    Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

    Part of Neuroscience, p. 172-183, 2019.

    Open access
  • Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

    Correlations between sex-related hormones, alcohol dependence and alcohol craving

    Part of Drug And Alcohol Dependence, p. 183-190, 2019.

    Open access
  • Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

    A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

    Part of ChemistryOpen, p. 114-125, 2019.

    Open access
  • Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

    Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

    Part of American Journal of Psychiatry, p. 146-155, 2019.

  • Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

    Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

    Part of Restorative Neurology and Neuroscience, p. 87-96, 2019.

    Open access
  • Mueller, Christian P.; Chu, Congying; Qin, Liya; Liu, Chunyu et al.

    The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

    Part of Cerebral Cortex, p. 1736-1751, 2019.

    Open access
  • Wallinder, Charlotta; Sköld, Christian; Sundholm, Sara; Guimond, Marie-Odile et al.

    High affinity rigidified AT(2) receptor ligands with indane scaffolds

    Part of MedChemComm, p. 2146-2160, 2019.

    Open access
  • Meng, Weida; Sjöholm, Louise K; Kononenko, Olga; Tay, Nicole et al.

    Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.

    Part of Molecular Psychiatry, 2019.

  • Jia, Tianye; Chu, Congying; Liu, Yun; van Dongen, Jenny et al.

    Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.

    Part of Molecular Psychiatry, 2019.

  • Duarte, Joana; Fernandes, Elisabete C.; Kononenko, Olga; Sarkisyan, Daniil et al.

    Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

    Part of Brain Research, p. 182-189, 2019.

  • Ruggeri, Barbara; Macare, Christine; Stopponi, Serena; Jia, Tianye et al.

    Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

    Part of Journal of Child Psychology and Psychiatry and Allied Disciplines, p. 50-658, 2018.

  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

    Part of Translational Psychiatry, 2018.

    Open access
  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

    Part of Molecular Neurobiology, p. 7049-7061, 2018.

    Open access
  • Kononenko, Olga; Mityakina, Irina; Galatenko, Vladimir; Watanabe, Hiroyuki et al.

    Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

    Part of Brain Research, p. 78-83, 2018.

  • Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Thelin, Jonas et al.


    Part of Journal of Neurotrauma, p. A208-A208, 2018.

  • Watanabe, Hiroyuki; Zhang, Mengliang; Sarkisyan, Daniil; Kononenko, Olga et al.

    Asymmetric Hindlimb Motor Response To Focal Traumatic Brain Injury Is Controlled By Side-Specific Opioid Mechanism

    Part of Journal of Neurotrauma, p. A79-A79, 2018.

  • Lukoyanov, Nikolay; Carvalho, Liliana; Watanabe, Hiroyuki; Zhang, Mengliang et al.

    Contralesional Hindlimb Motor Response Induced By Unilateral Brain Injury: Evidence For Extra Spinal Mechanism

    Part of Journal of Neurotrauma, p. A201-A201, 2018.

  • Nylander, Erik; Zelleroth, Sofia; Nyberg, Fred; Grönbladh, Alfhild et al.

    The Protective and Restorative Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Methadone-Induced Toxicity In Vitro

    Part of International Journal of Molecular Sciences, p. 1-16, 2018.

    Open access
  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

    Part of Cerebral Cortex, p. 3129-3142, 2018.

  • Brolin, Erika; Zelleroth, Sofia; Jonsson, Anna; Hallberg, Mathias et al.

    Chronic administration of morphine using mini-osmotic pumps affects spatial memory in the male rat

    Part of Pharmacology, Biochemistry and Behavior, p. 1-8, 2018.

  • Skogh, Anna; Lesniak, Anna; Sköld, Christian; Karlgren, Maria et al.

    An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

    Part of Bioorganic & Medicinal Chemistry Letters, p. 2446-2450, 2018.

  • Wannberg, Johan; Isaksson, Rebecka; Bremberg, Ulf; Backlund, Maria et al.

    A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

    Part of Bioorganic & Medicinal Chemistry Letters, p. 519-522, 2018.

  • Reddy Vanga, Sudarsana; Sävmarker, Jonas; Ng, Leelee; Larhed, Mats et al.

    Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

    Part of ACS Omega, p. 4509-4521, 2018.

    Open access
  • Ahmed, Aisha S.; Gedin, Per; Hugo, Anders; Bakalkin, Georgy et al.

    Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

    Part of Journal of Immunology, p. 1918-1927, 2018.

  • Kononenko, Olga; Bazov, Igor; Watanabe, Hiroyuki; Gerashchenko, Ganna et al.

    Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

    Part of Biochimica et Biophysica Acta, p. 246-255, 2017.

  • Sarkisyan, Daniil; Bazov, Igor; Watanabe, Hiroyuki; Kononenko, Olga et al.

    Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation

    Part of Acta Neuropathologica, p. 485-487, 2017.

  • Ahmed, Aisha Siddiqah; Ahmed, Mahmood; Li, Jian; Gu, Harvest F et al.

    Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis.

    Part of International journal of rheumatic diseases, p. 25-32, 2017.

  • Bivehed, Erik; Strömvall, Robert; Bergquist, Jonas; Bakalkin, Georgy et al.

    Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry

    Part of Peptides, p. 20-27, 2017.

    Open access
  • Sui, Ping; Watanabe, Hiroyuki; Artemenko, Konstantin; Sun, Wei et al.

    Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies

    Part of European journal of mass spectrometry, p. 105-115, 2017.