Senaste publikationer
-
Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
Ingår i Drug Metabolism and Pharmacokinetics, 2023.
Artikel i tidskrift
DOI för Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
-
Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
Ingår i Biomedicine and Pharmacotherapy, 2023.
Artikel, forskningsöversikt
DOI för Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation Ladda ner fulltext (pdf) av Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
-
Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
Ingår i Scientific Reports, 2023.
Artikel i tidskrift
DOI för Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma Ladda ner fulltext (pdf) av Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
-
Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions.
Ingår i European Journal of Haematology, 2023.
Artikel i tidskrift
DOI för Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions. Ladda ner fulltext (pdf) av Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions.
-
Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats
Ingår i Basic & Clinical Pharmacology & Toxicology, s. 507-516, 2023.
Artikel i tidskrift
DOI för Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats Ladda ner fulltext (pdf) av Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats
-
The progression of doxorubicin-induced intestinal mucositis in rats
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. 247-260, 2023.
Artikel i tidskrift
DOI för The progression of doxorubicin-induced intestinal mucositis in rats Ladda ner fulltext (pdf) av The progression of doxorubicin-induced intestinal mucositis in rats
-
Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
Ingår i International Journal of Molecular Sciences, 2022.
Artikel i tidskrift
DOI för Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats Ladda ner fulltext (pdf) av Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
-
Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
Ingår i Cells, 2022.
Artikel i tidskrift
DOI för Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
-
Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
Ingår i Pharmaceutics, 2022.
Artikel, forskningsöversikt
DOI för Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research Ladda ner fulltext (pdf) av Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
-
Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
Ingår i European Journal of Pharmaceutical Sciences, 2022.
Artikel, forskningsöversikt
DOI för Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review Ladda ner fulltext (pdf) av Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
-
Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
Ingår i Metabolites, 2022.
Artikel i tidskrift
DOI för Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding Ladda ner fulltext (pdf) av Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
-
Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
Ingår i Basic & Clinical Pharmacology & Toxicology, 2022.
Artikel i tidskrift
DOI för Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats Ladda ner fulltext (pdf) av Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
-
Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
Ingår i European Journal of Pharmaceutical Sciences, 2022.
Artikel i tidskrift
DOI för Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue Ladda ner fulltext (pdf) av Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
-
Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
Ingår i BMJ Open, 2022.
Artikel i tidskrift
DOI för Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival Ladda ner fulltext (pdf) av Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
-
Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
Ingår i CPT, s. 1194-1209, 2022.
Artikel i tidskrift
DOI för Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction Ladda ner fulltext (pdf) av Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
-
Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2022.
Artikel i tidskrift
DOI för Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats Ladda ner fulltext (pdf) av Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
-
Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
Ingår i Frontiers in Medicine, 2021.
Artikel, forskningsöversikt
DOI för Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare Ladda ner fulltext (pdf) av Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
-
Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
Ingår i Frontiers in Pharmacology, 2021.
Artikel, forskningsöversikt
DOI för Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies Ladda ner fulltext (pdf) av Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
-
Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 240-251, 2021.
Artikel i tidskrift
DOI för Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability Ladda ner fulltext (pdf) av Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
-
Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
Ingår i Cells, 2021.
Artikel i tidskrift
DOI för Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death Ladda ner fulltext (pdf) av Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
-
Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
Ingår i International Journal of Molecular Sciences, 2021.
Artikel, forskningsöversikt
DOI för Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
-
In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
Ingår i Cells, 2021.
Artikel i tidskrift
DOI för In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
-
Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
Ingår i Acta Pharmaceutica Sinica B, s. 1667-1675, 2021.
Artikel i tidskrift
DOI för Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats Ladda ner fulltext (pdf) av Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
-
Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2021.
Artikel i tidskrift
DOI för Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats Ladda ner fulltext (pdf) av Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
-
ICH M9 Guideline in Development on Biopharmaceutics Classification System-Based Biowaivers: An Industrial Perspective from the IQ Consortium
Ingår i Molecular Pharmaceutics, s. 361-372, 2020.
Artikel i tidskrift
-
The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
Ingår i Pharmaceutics, 2020.
Artikel i tidskrift
DOI för The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin Ladda ner fulltext (pdf) av The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
-
Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
Ingår i Pharmaceutics, 2020.
Artikel i tidskrift
DOI för Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat Ladda ner fulltext (pdf) av Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
-
Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 236-247, 2020.
Artikel i tidskrift
-
Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models
Ingår i ADMET & DMPK, s. 375-390, 2020.
Artikel, forskningsöversikt
DOI för Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models Ladda ner fulltext (pdf) av Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models
-
Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
Ingår i Obesity Science & Practice, s. 313-323, 2020.
Artikel i tidskrift
DOI för Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity Ladda ner fulltext (pdf) av Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
-
Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications
Ingår i European Journal of Pharmaceutical Sciences, 2020.
Artikel i tidskrift
DOI för Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications Ladda ner fulltext (pdf) av Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications
-
Pulmonary drug absorption and systemic exposure in human: Predictions using physiologically based biopharmaceutics modeling
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 191-202, 2020.
Artikel i tidskrift
-
The Critical Role of Passive Permeability in Designing Successful Drugs
Ingår i ChemMedChem, s. 1862-1874, 2020.
Artikel, forskningsöversikt
DOI för The Critical Role of Passive Permeability in Designing Successful Drugs
-
Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol
Ingår i International Journal of Molecular Sciences, 2020.
Artikel i tidskrift
DOI för Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol Ladda ner fulltext (pdf) av Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol
-
Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption
Ingår i AAPS Journal, 2020.
Artikel i tidskrift
DOI för Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption Ladda ner fulltext (pdf) av Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption
-
Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective
Ingår i Molecules, 2020.
Artikel, forskningsöversikt
DOI för Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective Ladda ner fulltext (pdf) av Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective
-
Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations
Ingår i Applied Sciences, 2020.
Artikel i tidskrift
DOI för Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations Ladda ner fulltext (pdf) av Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations
-
Physiologically based pharmacokinetic model predictions of ivosidenib (AG-120) as a victim and perpetrator of drug–drug interactions
Ingår i Drug Metabolism and Pharmacokinetics, s. S70-S71, 2019.
Artikel i tidskrift
-
Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches
Ingår i Pharmaceutics, 2019.
Artikel, forskningsöversikt
DOI för Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches Ladda ner fulltext (pdf) av Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches
-
Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 411-420, 2019.
Artikel i tidskrift
-
Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 387-395, 2019.
Artikel i tidskrift
-
Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 31-37, 2019.
Artikel i tidskrift
-
Rat intestinal drug permeability: A status report and summary of repeated determinations
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 364-376, 2019.
Artikel i tidskrift
DOI för Rat intestinal drug permeability: A status report and summary of repeated determinations
-
Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model
Ingår i Molecular Pharmaceutics, s. 3053-3064, 2019.
Artikel i tidskrift
DOI för Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model
-
Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile
Ingår i Cancers, 2019.
Artikel i tidskrift
DOI för Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile Ladda ner fulltext (pdf) av Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile
-
Lipiodol-based emulsions used for transarterial chemoembolization and drug delivery: Effects of composition on stability and product quality
Ingår i Journal of Drug Delivery Science and Technology, 2019.
Artikel i tidskrift
DOI för Lipiodol-based emulsions used for transarterial chemoembolization and drug delivery: Effects of composition on stability and product quality Ladda ner fulltext (pdf) av Lipiodol-based emulsions used for transarterial chemoembolization and drug delivery: Effects of composition on stability and product quality
-
Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'"
Ingår i Molecular Pharmaceutics, s. 336-340, 2018.
Artikel i tidskrift
-
Pulmonary absorption - estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex vivo rat model and computational analysis
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 1-12, 2018.
Artikel i tidskrift
-
The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs.
Ingår i International Journal of Pharmaceutics, s. 158-168, 2018.
Artikel i tidskrift
-
Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport.
Ingår i International Journal of Pharmaceutics, s. 239-248, 2018.
Artikel i tidskrift