Senaste publikationer
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The progression of doxorubicin-induced intestinal mucositis in rats
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. 247-260, 2023.
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DOI för The progression of doxorubicin-induced intestinal mucositis in rats Ladda ner fulltext (pdf) av The progression of doxorubicin-induced intestinal mucositis in rats
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Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
Ingår i Frontiers in Pharmacology, 2023.
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DOI för Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development Ladda ner fulltext (pdf) av Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
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Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
Ingår i Drug Metabolism and Pharmacokinetics, 2023.
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DOI för Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
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Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
Ingår i Biomedicine and Pharmacotherapy, 2023.
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DOI för Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation Ladda ner fulltext (pdf) av Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
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Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development
Ingår i Frontiers in Pharmacology, 2023.
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DOI för Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development Ladda ner fulltext (pdf) av Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development
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Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
Ingår i International Journal of Molecular Sciences, 2022.
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DOI för Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats Ladda ner fulltext (pdf) av Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
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Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
Ingår i Cells, 2022.
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DOI för Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
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Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2022.
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DOI för Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats Ladda ner fulltext (pdf) av Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
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Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)
Ingår i BMJ Open, 2022.
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DOI för Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP) Ladda ner fulltext (pdf) av Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)
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Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis
Ingår i Pharmaceutics, 2022.
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DOI för Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis Ladda ner fulltext (pdf) av Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis
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Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
Ingår i Pharmaceutics, 2022.
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DOI för Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research Ladda ner fulltext (pdf) av Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
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Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial
Ingår i American Journal of Respiratory and Critical Care Medicine, s. 1228-1235, 2022.
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Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
Ingår i European Journal of Pharmaceutical Sciences, 2022.
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DOI för Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review Ladda ner fulltext (pdf) av Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
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Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial
Ingår i EClinicalMedicine, 2022.
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DOI för Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial Ladda ner fulltext (pdf) av Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial
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Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics
Ingår i Clinical Microbiology and Infection, s. 448.e1-448.e7, 2022.
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DOI för Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics Ladda ner fulltext (pdf) av Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics
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Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application
Ingår i CPT, s. 991-1001, 2022.
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DOI för Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application Ladda ner fulltext (pdf) av Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application
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Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
Ingår i Pharmaceutics, 2022.
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DOI för Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin Ladda ner fulltext (pdf) av Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
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A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study
Ingår i CPT, s. 628-639, 2022.
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DOI för A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study Ladda ner fulltext (pdf) av A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study
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Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data
Ingår i Journal of Infectious Diseases, s. 1876-1885, 2022.
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DOI för Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data Ladda ner fulltext (pdf) av Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data
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Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
Ingår i Metabolites, 2022.
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DOI för Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding Ladda ner fulltext (pdf) av Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
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Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
Ingår i Basic & Clinical Pharmacology & Toxicology, 2022.
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DOI för Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats Ladda ner fulltext (pdf) av Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
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Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
Ingår i BMJ Open, 2022.
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DOI för Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival Ladda ner fulltext (pdf) av Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
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Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
Ingår i Frontiers in Pharmacology, 2022.
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DOI för Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies Ladda ner fulltext (pdf) av Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
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Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
Ingår i CPT, s. 1194-1209, 2022.
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DOI för Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction Ladda ner fulltext (pdf) av Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
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Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
Ingår i European Journal of Pharmaceutical Sciences, 2022.
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DOI för Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue Ladda ner fulltext (pdf) av Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
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Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug
Ingår i CPT, s. 1628-1637, 2022.
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DOI för Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug Ladda ner fulltext (pdf) av Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug
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Pharmacometrics in tuberculosis: progress and opportunities
Ingår i International Journal of Antimicrobial Agents, 2022.
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DOI för Pharmacometrics in tuberculosis: progress and opportunities Ladda ner fulltext (pdf) av Pharmacometrics in tuberculosis: progress and opportunities
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Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
Ingår i Frontiers in Medicine, 2021.
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DOI för Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare Ladda ner fulltext (pdf) av Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
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Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
Ingår i Frontiers in Pharmacology, 2021.
Artikel, forskningsöversikt
DOI för Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies Ladda ner fulltext (pdf) av Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
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Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 240-251, 2021.
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DOI för Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability Ladda ner fulltext (pdf) av Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
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Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
Ingår i Cells, 2021.
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DOI för Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death Ladda ner fulltext (pdf) av Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
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Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
Ingår i ACTA PHARMACEUTICA SINICA B, s. 1667-1675, 2021.
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DOI för Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats Ladda ner fulltext (pdf) av Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
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Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.
Ingår i European Respiratory Journal, 2021.
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Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model
Ingår i Journal of Infectious Diseases, s. 1039-1047, 2021.
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Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
Ingår i International Journal of Molecular Sciences, 2021.
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DOI för Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
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Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2021.
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DOI för Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats Ladda ner fulltext (pdf) av Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
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In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
Ingår i Cells, 2021.
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DOI för In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
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ICH M9 Guideline in Development on Biopharmaceutics Classification System-Based Biowaivers: An Industrial Perspective from the IQ Consortium
Ingår i Molecular Pharmaceutics, s. 361-372, 2020.
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The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
Ingår i Pharmaceutics, 2020.
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DOI för The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin Ladda ner fulltext (pdf) av The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
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Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review
Ingår i JMIR mhealth and uhealth, 2020.
Artikel, forskningsöversikt
DOI för Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review
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Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
Ingår i Pharmaceutics, 2020.
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DOI för Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat Ladda ner fulltext (pdf) av Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
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Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients
Ingår i Antimicrobial Agents and Chemotherapy, 2020.
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DOI för Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients Ladda ner fulltext (pdf) av Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients
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Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations
Ingår i Applied Sciences, 2020.
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DOI för Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations Ladda ner fulltext (pdf) av Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations
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Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 236-247, 2020.
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Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example
Ingår i Frontiers in Pharmacology, 2020.
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DOI för Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example Ladda ner fulltext (pdf) av Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example
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Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective
Ingår i Molecules, 2020.
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DOI för Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective Ladda ner fulltext (pdf) av Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective
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Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development
Ingår i Clinical Pharmacology and Therapeutics, s. 1285-1289, 2020.
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Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models
Ingår i ADMET & DMPK, s. 375-390, 2020.
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DOI för Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models Ladda ner fulltext (pdf) av Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models
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Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
Ingår i Obesity Science & Practice, s. 313-323, 2020.
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DOI för Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity Ladda ner fulltext (pdf) av Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
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Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications
Ingår i European Journal of Pharmaceutical Sciences, 2020.
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DOI för Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications Ladda ner fulltext (pdf) av Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications