Senaste publikationer
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Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
Ingår i Frontiers in Pharmacology, 2023.
Artikel i tidskrift
DOI för Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development Ladda ner fulltext (pdf) av Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
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Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
Ingår i Drug Metabolism and Pharmacokinetics, 2023.
Artikel i tidskrift
DOI för Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus
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Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
Ingår i Biomedicine and Pharmacotherapy, 2023.
Artikel, forskningsöversikt
DOI för Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation Ladda ner fulltext (pdf) av Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation
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Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development
Ingår i Frontiers in Pharmacology, 2023.
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DOI för Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development Ladda ner fulltext (pdf) av Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development
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Early bactericidal activity studies for pulmonary tuberculosis: A systematic review of methodological aspects
Ingår i International Journal of Antimicrobial Agents, 2023.
Artikel, forskningsöversikt
DOI för Early bactericidal activity studies for pulmonary tuberculosis: A systematic review of methodological aspects Ladda ner fulltext (pdf) av Early bactericidal activity studies for pulmonary tuberculosis: A systematic review of methodological aspects
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Model-based analysis of bactericidal activity and a new dosing strategy for optimised-dose rifampicin
Ingår i International Journal of Antimicrobial Agents, 2023.
Artikel i tidskrift
DOI för Model-based analysis of bactericidal activity and a new dosing strategy for optimised-dose rifampicin Ladda ner fulltext (pdf) av Model-based analysis of bactericidal activity and a new dosing strategy for optimised-dose rifampicin
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Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
Ingår i Scientific Reports, 2023.
Artikel i tidskrift
DOI för Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma Ladda ner fulltext (pdf) av Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
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Clinical standards for the management of adverse effects during treatment for TB
Ingår i The International Journal of Tuberculosis and Lung Disease, s. 506-519, 2023.
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DOI för Clinical standards for the management of adverse effects during treatment for TB Ladda ner fulltext (pdf) av Clinical standards for the management of adverse effects during treatment for TB
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Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy
Ingår i CPT, s. 977-987, 2023.
Artikel i tidskrift
DOI för Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy Ladda ner fulltext (pdf) av Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy
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Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients
Ingår i Advances in Therapy, s. 3739-3750, 2023.
Artikel i tidskrift
DOI för Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients Ladda ner fulltext (pdf) av Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients
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Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions.
Ingår i European Journal of Haematology, 2023.
Artikel i tidskrift
DOI för Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions. Ladda ner fulltext (pdf) av Despite warnings, co-medication with proton pump inhibitors and dasatinib is common in chronic myeloid leukemia, but XS004, a novel oral dasatinib formulation, provides reduced pH-dependence, minimizing undesirable drug-drug interactions.
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Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats
Ingår i Basic & Clinical Pharmacology & Toxicology, s. 507-516, 2023.
Artikel i tidskrift
DOI för Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats Ladda ner fulltext (pdf) av Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats
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Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium
Ingår i iScience, 2023.
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DOI för Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium Ladda ner fulltext (pdf) av Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium
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Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium
Ingår i ISCIENCE, 2023.
Artikel i tidskrift
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The progression of doxorubicin-induced intestinal mucositis in rats
Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. 247-260, 2023.
Artikel i tidskrift
DOI för The progression of doxorubicin-induced intestinal mucositis in rats Ladda ner fulltext (pdf) av The progression of doxorubicin-induced intestinal mucositis in rats
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Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
Ingår i International Journal of Molecular Sciences, 2022.
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DOI för Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats Ladda ner fulltext (pdf) av Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
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Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
Ingår i Cells, 2022.
Artikel i tidskrift
DOI för Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
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Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis
Ingår i Pharmaceutics, 2022.
Artikel i tidskrift
DOI för Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis Ladda ner fulltext (pdf) av Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis
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Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
Ingår i Pharmaceutics, 2022.
Artikel, forskningsöversikt
DOI för Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research Ladda ner fulltext (pdf) av Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
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Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial
Ingår i American Journal of Respiratory and Critical Care Medicine, s. 1228-1235, 2022.
Artikel i tidskrift
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Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
Ingår i European Journal of Pharmaceutical Sciences, 2022.
Artikel, forskningsöversikt
DOI för Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review Ladda ner fulltext (pdf) av Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
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Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics
Ingår i Clinical Microbiology and Infection, s. 448.e1-448.e7, 2022.
Artikel i tidskrift
DOI för Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics Ladda ner fulltext (pdf) av Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics
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Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application
Ingår i CPT, s. 991-1001, 2022.
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DOI för Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application Ladda ner fulltext (pdf) av Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application
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Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
Ingår i Pharmaceutics, 2022.
Artikel i tidskrift
DOI för Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin Ladda ner fulltext (pdf) av Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
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A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study
Ingår i CPT, s. 628-639, 2022.
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DOI för A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study Ladda ner fulltext (pdf) av A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study
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Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data
Ingår i Journal of Infectious Diseases, s. 1876-1885, 2022.
Artikel i tidskrift
DOI för Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data Ladda ner fulltext (pdf) av Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data
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Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
Ingår i Metabolites, 2022.
Artikel i tidskrift
DOI för Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding Ladda ner fulltext (pdf) av Orthogonality in Principal Component Analysis Allows the Discovery of Lipids in the Jejunum That Are Independent of Ad Libitum Feeding
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Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
Ingår i Basic & Clinical Pharmacology & Toxicology, 2022.
Artikel i tidskrift
DOI för Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats Ladda ner fulltext (pdf) av Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
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Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
Ingår i Frontiers in Pharmacology, 2022.
Artikel, forskningsöversikt
DOI för Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies Ladda ner fulltext (pdf) av Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
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Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
Ingår i European Journal of Pharmaceutical Sciences, 2022.
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DOI för Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue Ladda ner fulltext (pdf) av Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue
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Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug
Ingår i CPT, s. 1628-1637, 2022.
Artikel i tidskrift
DOI för Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug Ladda ner fulltext (pdf) av Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug
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Pharmacometrics in tuberculosis: progress and opportunities
Ingår i International Journal of Antimicrobial Agents, 2022.
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DOI för Pharmacometrics in tuberculosis: progress and opportunities Ladda ner fulltext (pdf) av Pharmacometrics in tuberculosis: progress and opportunities
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Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial
Ingår i eClinicalMedicine, 2022.
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DOI för Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial Ladda ner fulltext (pdf) av Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial
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Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
Ingår i BMJ Open, 2022.
Artikel i tidskrift
DOI för Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival Ladda ner fulltext (pdf) av Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
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Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)
Ingår i BMJ Open, 2022.
Artikel i tidskrift
DOI för Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP) Ladda ner fulltext (pdf) av Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)
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Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
Ingår i CPT, s. 1194-1209, 2022.
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DOI för Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction Ladda ner fulltext (pdf) av Does the choice of applied physiologically-based pharmacokinetics platform matter?: A case study on simvastatin disposition and drug-drug interaction
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Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2022.
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DOI för Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats Ladda ner fulltext (pdf) av Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
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Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
Ingår i Frontiers in Medicine, 2021.
Artikel, forskningsöversikt
DOI för Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare Ladda ner fulltext (pdf) av Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare
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Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
Ingår i Frontiers in Pharmacology, 2021.
Artikel, forskningsöversikt
DOI för Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies Ladda ner fulltext (pdf) av Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
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Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 240-251, 2021.
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DOI för Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability Ladda ner fulltext (pdf) av Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
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Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
Ingår i Cells, 2021.
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DOI för Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death Ladda ner fulltext (pdf) av Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death
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Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.
Ingår i European Respiratory Journal, 2021.
Artikel i tidskrift
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Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model
Ingår i Journal of Infectious Diseases, s. 1039-1047, 2021.
Artikel i tidskrift
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Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
Ingår i International Journal of Molecular Sciences, 2021.
Artikel, forskningsöversikt
DOI för Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma
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In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
Ingår i Cells, 2021.
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DOI för In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma Ladda ner fulltext (pdf) av In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma
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Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
Ingår i Acta Pharmaceutica Sinica B, s. 1667-1675, 2021.
Artikel i tidskrift
DOI för Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats Ladda ner fulltext (pdf) av Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
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Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
Ingår i International Journal of Molecular Sciences, 2021.
Artikel i tidskrift
DOI för Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats Ladda ner fulltext (pdf) av Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
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ICH M9 Guideline in Development on Biopharmaceutics Classification System-Based Biowaivers: An Industrial Perspective from the IQ Consortium
Ingår i Molecular Pharmaceutics, s. 361-372, 2020.
Artikel i tidskrift
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The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
Ingår i Pharmaceutics, 2020.
Artikel i tidskrift
DOI för The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin Ladda ner fulltext (pdf) av The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
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Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review
Ingår i JMIR mhealth and uhealth, 2020.
Artikel, forskningsöversikt
DOI för Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review