Senaste publikationer

Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development

Ayoun Alsoud, Rami; Svensson, Robin J.; Svensson, Elin; Gillespie, Stephen H. H. et al.

Ingår i Frontiers in Pharmacology, 2023.

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DOI för Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development Ladda ner fulltext (pdf) av Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development

Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development

Mockeliunas, Laurynas; Faraj, Alan; Van Wijk, Rob C; Upton, Caryn M. et al.

Ingår i Frontiers in Pharmacology, 2023.

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DOI för Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development Ladda ner fulltext (pdf) av Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development

Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)

Ekqvist, David; Bornefall, Anna; Augustinsson, Daniel; Sönnerbrandt, Martina et al.

Ingår i BMJ Open, 2022.

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DOI för Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP) Ladda ner fulltext (pdf) av Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP)

Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis

Mockeliunas, Laurynas; Keutzer, Lina; Sturkenboom, Marieke G. G.; Bolhuis, Mathieu S. et al.

Ingår i Pharmaceutics, 2022.

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DOI för Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis Ladda ner fulltext (pdf) av Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis

Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

De Jager, Veronique; Gupte, Nikhil; Nunes, Silvia; Barnes, Grace L. et al.

Ingår i American Journal of Respiratory and Critical Care Medicine, s. 1228-1235, 2022.

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DOI för Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial

Upton, Caryn M.; Van Wijk, Rob C; Mockeliunas, Laurynas; Simonsson, Ulrika S. H. et al.

Ingår i EClinicalMedicine, 2022.

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DOI för Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial Ladda ner fulltext (pdf) av Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double- blind, randomised, controlled, phase 3 trial

Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics

Ruth, Mike Marvin; Raaijmakers, Jelmer; van den Hombergh, Erik; Aarnoutse, Rob et al.

Ingår i Clinical Microbiology and Infection, s. 448.e1-448.e7, 2022.

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DOI för Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics Ladda ner fulltext (pdf) av Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics

Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application

Van Wijk, Rob C; Simonsson, Ulrika S. H.

Ingår i CPT, s. 991-1001, 2022.

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DOI för Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application Ladda ner fulltext (pdf) av Finding the right hazard function for time-to-event modeling: A tutorial and Shiny application

Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin

Keutzer, Lina; You, Huifang; Farnoud, Ali; Nyberg, Joakim et al.

Ingår i Pharmaceutics, 2022.

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DOI för Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin Ladda ner fulltext (pdf) av Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin

A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study

Keutzer, Lina; Akhondipour, Yasamin; Forsman, Lina Davies; Simonsson, Ulrika S. H.

Ingår i CPT, s. 628-639, 2022.

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DOI för A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study Ladda ner fulltext (pdf) av A modeling-based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study

Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data

Mudde, Saskia E.; Ayoun Alsoud, Rami; van der Meijden, Aart; Upton, Anna M. et al.

Ingår i Journal of Infectious Diseases, s. 1876-1885, 2022.

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DOI för Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data Ladda ner fulltext (pdf) av Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data

Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

Sennefelt Nyman, Sofi; Ahlström, Håkan; Dimopoulou, Angeliki; Dahlgren, David et al.

Ingår i BMJ Open, 2022.

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DOI för Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival Ladda ner fulltext (pdf) av Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

Alffenaar, Jan-Willem C.; de Steenwinkel, Jurriaan E. M.; Diacon, Andreas H.; Simonsson, Ulrika S. H. et al.

Ingår i Frontiers in Pharmacology, 2022.

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DOI för Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies Ladda ner fulltext (pdf) av Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

Faraj, Alan; Knudsen, Tom; Desai, Shraddha; Neuman, Linda et al.

Ingår i CPT, s. 1628-1637, 2022.

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DOI för Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug Ladda ner fulltext (pdf) av Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

Pharmacometrics in tuberculosis: progress and opportunities

Wilkins, Justin J.; Svensson, Elin; Ernest, Jacqueline P.; Savic, Radojka M. et al.

Ingår i International Journal of Antimicrobial Agents, 2022.

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DOI för Pharmacometrics in tuberculosis: progress and opportunities Ladda ner fulltext (pdf) av Pharmacometrics in tuberculosis: progress and opportunities

Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.

Davies Forsman, Lina; Niward, Katarina; Kuhlin, Johanna; Zheng, Xubin et al.

Ingår i European Respiratory Journal, 2021.

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DOI för Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.

Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model

Pieterman, Elise D.; Keutzer, Lina; van der Meijden, Aart; van den Berg, Sanne et al.

Ingår i Journal of Infectious Diseases, s. 1039-1047, 2021.

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DOI för Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model

Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review

Keutzer, Lina; Wicha, Sebastian G.; Simonsson, Ulrika S H

Ingår i JMIR mhealth and uhealth, 2020.

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DOI för Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review

Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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DOI för Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients Ladda ner fulltext (pdf) av Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations

Van Wijk, Rob C; Ayoun Alsoud, Rami; Lennernäs, Hans; Simonsson, Ulrika S H

Ingår i Applied Sciences, 2020.

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DOI för Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations Ladda ner fulltext (pdf) av Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations

Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example

Keutzer, Lina; Simonsson, Ulrika S. H.

Ingår i Frontiers in Pharmacology, 2020.

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DOI för Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example Ladda ner fulltext (pdf) av Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example

Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development

Gupta, Neeraj; Bottino, Dean; Simonsson, Ulrika S H; Musante, Cynthia J. et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 1285-1289, 2020.

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DOI för Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development

Translational Model-Informed Approach for Selection of Tuberculosis Drug Combination Regimens in Early Clinical Development.

Susanto, Budi O.; Wicha, Sebastian G; Hu, Yanmin; Coates, Anthony R M et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 274-286, 2020.

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DOI för Translational Model-Informed Approach for Selection of Tuberculosis Drug Combination Regimens in Early Clinical Development. Ladda ner fulltext (pdf) av Translational Model-Informed Approach for Selection of Tuberculosis Drug Combination Regimens in Early Clinical Development.

Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development

Van Wijk, Rob C.; van der Sar, Astrid M.; Krekels, Elke H. J.; Verboom, Theo et al.

Ingår i Clinical and Translational Science, s. 1060-1064, 2020.

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DOI för Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development Ladda ner fulltext (pdf) av Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development

Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

Van Wijk, Rob C.; Hu, Wanbin; Dijkema, Sharka M.; Van den Berg, Dirk-Jan et al.

Ingår i British Journal of Pharmacology, s. 5518-5533, 2020.

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DOI för Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans Ladda ner fulltext (pdf) av Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

Rifampicin can be given as flat-dosing instead of weight-band dosing

Susanto, Budi Octasari; Svensson, Robin J.; Svensson, Elin M.; Aarnoutse, Rob et al.

Ingår i Clinical Infectious Diseases, s. 3055-3060, 2020.

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DOI för Rifampicin can be given as flat-dosing instead of weight-band dosing Ladda ner fulltext (pdf) av Rifampicin can be given as flat-dosing instead of weight-band dosing

Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

Selch Larsen, Malte; Vestergaard Juul, Rasmus; Zintner, Shannon M.; Kristensen, Annemarie T. et al.

Ingår i Haemophilia, s. 164-172, 2020.

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DOI för Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.

Clewe, Oskar; Faraj, Alan; Hu, Yanmin; Coates, Anthony R M et al.

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 421-430, 2020.

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DOI för A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis. Ladda ner fulltext (pdf) av A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.

Medical Device Apps: An Introduction to Regulatory Affairs for Developers

Keutzer, Lina; Simonsson, Ulrika S. H.

Ingår i JMIR mhealth and uhealth, 2020.

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DOI för Medical Device Apps: An Introduction to Regulatory Affairs for Developers Ladda ner fulltext (pdf) av Medical Device Apps: An Introduction to Regulatory Affairs for Developers

Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions

Faraj, Alan; Clewe, Oskar; Svensson, Robin J.; Mukamolova, Galina V. et al.

Ingår i Scientific Reports, 2020.

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DOI för Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions Ladda ner fulltext (pdf) av Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions

Individualised dosing algorithm and personalised treatment of high‐dose rifampicin for tuberculosis

Svensson, Robin J.; Niward, Katarina; Davies Forsman, Lina; Bruchfeld, Judith et al.

Ingår i British Journal of Clinical Pharmacology, s. 2341-2350, 2019.

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DOI för Individualised dosing algorithm and personalised treatment of high‐dose rifampicin for tuberculosis

Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture

Svensson, Robin J.; Sabiiti, Wilber; Kibiki, Gibson S.; Ntinginya, Nyanda E. et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2019.

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DOI för Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture

Consider ASCPT in Your End-of-Year Giving

Wyatt, David; Strauss, David; Ray, Balmiki; Mehta, Krina et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 17-21, 2019.

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Prediction of human pharmacokinetics of activated recombinant factor VII and B-domain truncated factor VIII from animal population pharmacokinetic models of haemophilia

Larsen, Malte Selch; Juul, Rasmus Vestergaard; Groth, Andreas Velsing; Simonsson, Ulrika S H et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 196-203, 2018.

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DOI för Prediction of human pharmacokinetics of activated recombinant factor VII and B-domain truncated factor VIII from animal population pharmacokinetic models of haemophilia

Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

Larsen, Malte Selch; Juul, Rasmus Vestergaard; Kreilgaard, Mads; Kristensen, Annemarie T. et al.

Ingår i European Journal of Pharmaceutical Sciences, s. 531-538, 2018.

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DOI för Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

Forecasting Clinical Dose-Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin

Wicha, Sebastian G.; Clewe, Oskar; Svensson, Robin J.; Gillespie, Stephen H. et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 1208-1218, 2018.

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DOI för Forecasting Clinical Dose-Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin Ladda ner fulltext (pdf) av Forecasting Clinical Dose-Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin

Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study

Forsman, Lina Davies; Niward, Katarina; Hu, Yi; Zheng, Rongrong et al.

Ingår i BMJ Open, 2018.

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DOI för Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study Ladda ner fulltext (pdf) av Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

Svensson, Robin J.; Aarnoutse, Rob E; Diacon, Andreas H; Dawson, Rodney et al.

Ingår i Clinical Pharmacology and Therapeutics, s. 674-683, 2018.

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DOI för A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses Ladda ner fulltext (pdf) av A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations

Svensson, Robin J.; Svensson, Elin; Aarnoutse, Rob E.; Diacon, Andreas H. et al.

Ingår i Journal of Infectious Diseases, s. 991-999, 2018.

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DOI för Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations

The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis

Svensson, Elin M.; Svensson, Robin J.; te Brake, Lindsey H. M.; Boeree, Martin J. et al.

Ingår i Clinical Infectious Diseases, s. 34-41, 2018.

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DOI för The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis Ladda ner fulltext (pdf) av The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis

Distribution of plasma concentrations of first-line anti-TB drugs and individual MICs: a prospective cohort study in a low endemic setting

Niward, Katarina; Forsman, Lina Davies; Bruchfeld, Judith; Chryssanthou, Erja et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 2838-2845, 2018.

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DOI för Distribution of plasma concentrations of first-line anti-TB drugs and individual MICs: a prospective cohort study in a low endemic setting

A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations

Clewe, Oskar; Wicha, Sebastian G.; de Vogel, Corne P.; de Steenwinkel, Jurriaan E. M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 437-447, 2018.

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DOI för A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations Ladda ner fulltext (pdf) av A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations

Comparisons of analysis methods for assessment of pharmacodynamic interactions including design recommendations

Chen, Chunli; Wicha, Sebastian G.; Nordgren, Rikard; Simonsson, Ulrika S H

Ingår i AAPS Journal, 2018.

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DOI för Comparisons of analysis methods for assessment of pharmacodynamic interactions including design recommendations Ladda ner fulltext (pdf) av Comparisons of analysis methods for assessment of pharmacodynamic interactions including design recommendations

Improving treatment outcome assessment in a mouse tuberculosis model

Mourik, Bas C.; Svensson, Robin J.; de Knegt, Gerjo J.; Bax, Hannelore I. et al.

Ingår i Scientific Reports, 2018.

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DOI för Improving treatment outcome assessment in a mouse tuberculosis model Ladda ner fulltext (pdf) av Improving treatment outcome assessment in a mouse tuberculosis model

The implications of model-informed drug discovery and development for tuberculosis

Muliaditan, Morris; Davies, Geraint R.; Simonsson, Ulrika S.H.; Gillespie, Stephen H. et al.

Ingår i Drug Discovery Today, s. 481-486, 2017.

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DOI för The implications of model-informed drug discovery and development for tuberculosis

Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

Juul, Rasmus Vestergaard; Nyberg, Joakim; Kreilgaard, Mads; Christrup, Lona Louring et al.

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 325-333, 2017.

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DOI för Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

Assessing Pharmacodynamic Interactions in Mice using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models

Chen, Chunli; Wicha, Sebastian G.; de Knegt, Gerjo; Ortega, Fatima et al.

Ingår i CPT, s. 787-797, 2017.

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DOI för Assessing Pharmacodynamic Interactions in Mice using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models Ladda ner fulltext (pdf) av Assessing Pharmacodynamic Interactions in Mice using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models

Improved power for TB Phase IIa trials using a model-based pharmacokinetic-pharmacodynamic approach compared with commonly used analysis methods

Svensson, Robin J.; Gillespie, Stephen H.; Simonsson, Ulrika S. H.

Ingår i Journal of Antimicrobial Chemotherapy, s. 2311-2319, 2017.

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DOI för Improved power for TB Phase IIa trials using a model-based pharmacokinetic-pharmacodynamic approach compared with commonly used analysis methods Ladda ner fulltext (pdf) av Improved power for TB Phase IIa trials using a model-based pharmacokinetic-pharmacodynamic approach compared with commonly used analysis methods

Residual Spinal Cord Compression Following Hemilaminectomy and Mini-Hemilaminectomy in Dogs: A Prospective Randomized Study

Svensson, Gustaf; Simonsson, Ulrika S H; Danielsson, Fredrik; Schwarz, Tobias

Ingår i Frontiers in Veterinary Science, 2017.

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DOI för Residual Spinal Cord Compression Following Hemilaminectomy and Mini-Hemilaminectomy in Dogs: A Prospective Randomized Study

A Pharmacokinetic-Pharmacodynamic Model of Morphine Exposure and Subsequent Morphine Consumption in Postoperative Pain

Juul, Rasmus Vestergaard; Nyberg, Joakim; Lund, Trine Meldgaard; Rasmussen, Sten et al.

Ingår i Pharmaceutical research, s. 1093-1103, 2016.

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DOI för A Pharmacokinetic-Pharmacodynamic Model of Morphine Exposure and Subsequent Morphine Consumption in Postoperative Pain