Senaste publikationer

Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads

Muhammad, Taj; Strömstedt, Adam A.; Gunasekera, Sunithi; Göransson, Ulf

Ingår i Biomedicines, 2023.

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DOI för Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads Ladda ner fulltext (pdf) av Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads

Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclization of PawS-derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1

Muhammad, Taj; Houssen, E. Wael; Thomas, Louise; Alexandru-Crivac, Cristina-Nicoleta et al.

Ingår i Journal of Natural Products, s. 566-573, 2023.

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DOI för Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclization of PawS-derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1 Ladda ner fulltext (pdf) av Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclization of PawS-derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1

Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from Geophila repens

Rajendran, Sanjeevan; Slazak, Blazej; Mohotti, Supun; Muhammad, Taj et al.

Ingår i Journal of Natural Products, s. 52-65, 2023.

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DOI för Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from Geophila repens Ladda ner fulltext (pdf) av Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from Geophila repens

Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens

Rajendran, Sanjeevan; Robertson, Luke P.; Kosgahakumbura, Lakmini; Fernando, Chathurika et al.

Ingår i Fitoterapia, 2023.

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DOI för Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens Ladda ner fulltext (pdf) av Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens

The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Shariatgorji, Reza et al.

Ingår i PLANTS, 2022.

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DOI för The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures Ladda ner fulltext (pdf) av The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures

The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Sybilska, Anna et al.

Ingår i Scientific Reports, 2022.

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DOI för The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite Ladda ner fulltext (pdf) av The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite

A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens

White, John Kerr; Muhammad, Taj; Alsheim, Emelie; Mohanty, Soumitra et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022.

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DOI för A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens Ladda ner fulltext (pdf) av A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens

Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum

Safa, Neda; Trobec, Tomaz.; Holland, Darren C.; Slazak, Blazej et al.

Ingår i Journal of Natural Products, s. 215-224, 2022.

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DOI för Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum Ladda ner fulltext (pdf) av Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum

Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis

Jakobsson, Per-Johan; Robertson, Luke; Welzel, Janika; Zhang, Mingshu et al.

Ingår i Journal of Internal Medicine, s. 745-763, 2022.

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DOI för Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis Ladda ner fulltext (pdf) av Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis

Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules

Uddin, Shaikh Jamal; Shilpi, Jamil Ahmad; Nahar, Lutfun; Sarker, Satyajit D. et al.

Ingår i Frontiers in Pharmacology, 2021.

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DOI för Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules Ladda ner fulltext (pdf) av Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules

Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis

Rajendran, Sanjeevan; Slazak, Blazej; Mohotti, Supun; Strömstedt, Adam A. et al.

Ingår i Phytochemistry, 2021.

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DOI för Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis Ladda ner fulltext (pdf) av Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis

Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm

Zihad, S. M. Neamul Kabir; Uddin, Shaikh Jamal; Sifat, Nazifa; Lovely, Farhana et al.

Ingår i Biochemistry and Biophysics Reports, 2021.

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DOI för Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm Ladda ner fulltext (pdf) av Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm

Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates

Shcherbakova, A.; Strömstedt, Adam A.; Göransson, Ulf; Gnezdilov, O. et al.

Ingår i World Journal of Microbiology & Biotechnology, 2021.

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DOI för Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates Ladda ner fulltext (pdf) av Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates

Exploring natural products-based cancer therapeutics derived from egyptian flora

El-Seedi, Hesham; Yosri, Nermeen; Khalifa, Shaden A. M.; Guo, Zhiming et al.

Ingår i Journal of Ethnopharmacology, 2021.

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DOI för Exploring natural products-based cancer therapeutics derived from egyptian flora

Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

Wang, Si-Yu; Zhao, Hui; Xu, Hong-Tao; Han, Xiao-Dong et al.

Ingår i Frontiers in Pharmacology, 2021.

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DOI för Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses Ladda ner fulltext (pdf) av Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

Functional characterization of the nemertide alpha family of peptide toxins

Jacobsson, Erik; Peigneur, Steve; Andersson, Håkan; Laborde, Quentin et al.

Ingår i Journal of Natural Products, s. 2121-2128, 2021.

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DOI för Functional characterization of the nemertide alpha family of peptide toxins

Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti

Steffen, Karin; Laborde, Quentin; Gunasekera, Sunithi; Payne, Colton D. et al.

Ingår i Journal of Natural Products, s. 3138-3146, 2021.

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DOI för Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti Ladda ner fulltext (pdf) av Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti

Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides

Payne, Colton D.; Vadlamani, Grishma; Hajiaghaalipour, Fatemeh; Muhammad, Taj et al.

Ingår i RSC CHEMICAL BIOLOGY, s. 1682-1691, 2021.

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DOI för Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides Ladda ner fulltext (pdf) av Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides

Cyclotide host-defense tailored for species and environments in violets from the Canary Islands

Slazak, Blazej; Kaltenböck, Klara; Steffen, Karin; Rogala, Martyna et al.

Ingår i Scientific Reports, 2021.

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DOI för Cyclotide host-defense tailored for species and environments in violets from the Canary Islands Ladda ner fulltext (pdf) av Cyclotide host-defense tailored for species and environments in violets from the Canary Islands

Recent insights into chemical and pharmacological studies of bee bread

Khalifa, Shaden A. M.; Elashal, Mohamed; Kieliszek, Marek; Ghazala, Naglaa E. et al.

Ingår i Trends in Food Science & Technology, s. 300-316, 2020.

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DOI för Recent insights into chemical and pharmacological studies of bee bread

Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects

Afroz, Mohasana; Akter, Sanzida; Ahmed, Asif; Rouf, Razina et al.

Ingår i Frontiers in Pharmacology, 2020.

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DOI för Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects Ladda ner fulltext (pdf) av Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects

Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability

Gunasekera, Sunithi; Muhammad, Taj; Strömstedt, Adam A.; Rosengren, K. Johan et al.

Ingår i Frontiers in Microbiology, 2020.

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DOI för Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability Ladda ner fulltext (pdf) av Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability

Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae)

Robertson, Luke P.; Moodie, Lindon W. K.; Holland, Darren C.; Jandér, K. Charlotte et al.

Ingår i Journal of Natural Products, s. 1305-1308, 2020.

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DOI för Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae) Ladda ner fulltext (pdf) av Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae)

The life cycle of cyclotides: biosynthesis and turnover in plant cells

Slazak, Blazej; Haugmo, Tobias; Badyra, Bogna; Göransson, Ulf

Ingår i Plant Cell Reports, s. 1359-1367, 2020.

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DOI för The life cycle of cyclotides: biosynthesis and turnover in plant cells Ladda ner fulltext (pdf) av The life cycle of cyclotides: biosynthesis and turnover in plant cells

Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens

Mohotti, Supun; Rajendran, Sanjeevan; Muhammad, Taj; Strömstedt, Adam A. et al.

Ingår i Journal of Ethnopharmacology, 2020.

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DOI för Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens Ladda ner fulltext (pdf) av Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens

The Toxins of Nemertean Worms

Göransson, Ulf; Jacobsson, Erik; Strand, Malin; Andersson, Hakan S.

Ingår i Toxins, 2019.

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DOI för The Toxins of Nemertean Worms Ladda ner fulltext (pdf) av The Toxins of Nemertean Worms

Marine Natural Products: A Source of Novel Anticancer Drugs

Khalifa, Shaden A. M.; Elias, Nizar; Farag, Mohamed A.; Chen, Lei et al.

Ingår i Marine Drugs, 2019.

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DOI för Marine Natural Products: A Source of Novel Anticancer Drugs Ladda ner fulltext (pdf) av Marine Natural Products: A Source of Novel Anticancer Drugs

Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

Gunasekera, Sunithi; Fernandes-Cerqueira, Catia; Wennmalm, Stefan; Wahamaa, Heidi et al.

Ingår i ACS Chemical Biology, s. 1525-1535, 2018.

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DOI för Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System

Slazak, Blazej; Kapusta, Malgorzata; Strömstedt, Adam A.; Slomka, Aneta et al.

Ingår i Frontiers in Plant Science, 2018.

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DOI för How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System Ladda ner fulltext (pdf) av How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System

Repertoire Studies in Rheumatoid Arthritis Reveal B-Cell Distortions and Baseline Shifts in Unmutated IgG

Wang, Yan; Lloyd, Katy A.; Gunasekera, Sunithi; Eriksson, Camilla et al.

Ingår i Arthritis & Rheumatology, 2018.

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Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity

Gunasekera, Sunithi; Muhammad, Taj; Strömstedt, Adam A.; Rosengren, K. Johan et al.

Ingår i ChemBioChem (Print), s. 931-939, 2018.

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DOI för Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

Jacobsson, Erik; Andersson, Håkan S.; Strand, Malin; Peigneur, Steve et al.

Ingår i Scientific Reports, 2018.

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DOI för Peptide ion channel toxins from the bootlace worm, the longest animal on Earth Ladda ner fulltext (pdf) av Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

Single-step purification of cyclotides using affinity chromatography

Uddin, Shaikh Jamal; Muhammad, Taj; Shafiullah, Md; Slazak, Blazej et al.

Ingår i Biopolymers, 2017.

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DOI för Single-step purification of cyclotides using affinity chromatography

Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides

Malik, Sohaib Zafar; Linkevicius, Marius; Göransson, Ulf; Andersson, Dan I

Ingår i Antimicrobial Agents and Chemotherapy, 2017.

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DOI för Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides Ladda ner fulltext (pdf) av Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides

The "PepSAVI-MS" Pipeline for Natural Product Bioactive Peptide Discovery

Kirkpatrick, Christine L.; Broberg, Christopher A.; McCool, Elijah N.; Lee, Woo Jean et al.

Ingår i Analytical Chemistry, s. 1194-1201, 2017.

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DOI för The "PepSAVI-MS" Pipeline for Natural Product Bioactive Peptide Discovery

Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins

Hellinger, Roland; Thell, Kathrin; Vasileva, Mina; Muhammad, Taj et al.

Ingår i Frontiers in Chemistry, 2017.

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DOI för Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins Ladda ner fulltext (pdf) av Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins

Cyclotide Evolution: Insights from the Analyses of Their Precursor Sequences, Structures and Distribution in Violets (Viola)

Park, Sungkyu; Yoo, Ki-Oug; Marcussen, Thomas; Backlund, Anders et al.

Ingår i Frontiers in Plant Science, 2017.

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DOI för Cyclotide Evolution: Insights from the Analyses of Their Precursor Sequences, Structures and Distribution in Violets (Viola) Ladda ner fulltext (pdf) av Cyclotide Evolution: Insights from the Analyses of Their Precursor Sequences, Structures and Distribution in Violets (Viola)

Bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra

Strömstedt, Adam A.; Park, Sungkyu; Burman, Robert; Göransson, Ulf

Ingår i Biochimica et Biophysica Acta - Biomembranes, s. 1986-2000, 2017.

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DOI för Bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra

35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Bohlin, Lars; Cárdenas, Paco; Backlund, Anders; Göransson, Ulf

Ingår i Progress in molecular and subcellular biology, s. 1-34, 2017.

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DOI för 35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters.

Engineering Of A Minimalized Domain Derived From Human Host Defense Peptide LL-37 Into A Stable And Potent Antimicrobial Drug Lead

Muhammad, Taj; Gunasekera, Sunithi; Strömstedt, Adam A.; Göransson, Ulf

Ingår i Journal of Peptide Science, s. S184-S186, 2016.

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DOI för Engineering Of A Minimalized Domain Derived From Human Host Defense Peptide LL-37 Into A Stable And Potent Antimicrobial Drug Lead

Anti-Citrullinated Peptide Antibody Inhibitors Based On Sunflower Trypsin Inhibitor-1 Scaffold For Potential Anti-Rheumatoid Arthritis Activity

Gunasekera, Sunithi; Fernandes-Cerqueira, C.; Eriksson, Camilla; Jakobsson, P-J et al.

Ingår i Journal of Peptide Science, s. S170-S170, 2016.

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DOI för Anti-Citrullinated Peptide Antibody Inhibitors Based On Sunflower Trypsin Inhibitor-1 Scaffold For Potential Anti-Rheumatoid Arthritis Activity

Bacterial Resistance To A Cyclic Antimicrobial Peptide

Malik, Sohaib Zafar; Göransson, Ulf; Andersson, Dan I

Ingår i Journal of Peptide Science, s. S180-S180, 2016.

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DOI för Bacterial Resistance To A Cyclic Antimicrobial Peptide

Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis.

Thell, Kathrin; Hellinger, Roland; Sahin, Emine; Michenthaler, Paul et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 3960-3965, 2016.

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DOI för Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis.

Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket

Strömstedt, Adam A.; Kristiansen, Per Eugen; Gunasekera, Sunithi; Grob, Nathalie et al.

Ingår i Biochimica et Biophysica Acta, s. 1317-1327, 2016.

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DOI för Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket

The Bacterial (Vibrio alginolyticus) Production of Tetrodotoxin in the Ribbon Worm Lineus longissimus-Just a False Positive?

Strand, Malin; Hedström, Martin; Seth, Henrik; McEvoy, Eric G et al.

Ingår i Marine Drugs, 2016.

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DOI för The Bacterial (Vibrio alginolyticus) Production of Tetrodotoxin in the Ribbon Worm Lineus longissimus-Just a False Positive? Ladda ner fulltext (pdf) av The Bacterial (Vibrio alginolyticus) Production of Tetrodotoxin in the Ribbon Worm Lineus longissimus-Just a False Positive?

Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: An IUPAC task group interim report

Craik, David J.; Shim, Youn Young; Göransson, Ulf; Moss, Gerard P. et al.

Ingår i Biopolymers, s. 917-924, 2016.

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DOI för Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: An IUPAC task group interim report

Engineering of KR-12: A minimalized domain derived from human host defense peptide LL-37 into a potent antimicrobial drug lead

Muhammad, Taj; Gunasekera, Sunithi; Strömstedt, Adam A.; Göransson, Ulf

Ingår i Planta Medica, 2016.

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DOI för Engineering of KR-12: A minimalized domain derived from human host defense peptide LL-37 into a potent antimicrobial drug lead

Peptide toxins from the longest animal on earth

Jacobsson, Erik; Andersson, H. S.; Strand, M.; Lebbe, E. et al.

Ingår i Planta Medica, 2016.

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DOI för Peptide toxins from the longest animal on earth

Peptide biodiscovery from plants and animals: structure to function

Göransson, Ulf; Gunasekera, Sunithi; Malik, S.; Park, S. et al.

Ingår i Planta Medica, 2016.

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DOI för Peptide biodiscovery from plants and animals: structure to function

Circular disulfide-rich peptide scaffolds as anti-citrullinated peptide antibody inhibitors

Gunasekera, Sunithi; Fernandes-Cerqueira, C.; Eriksson, Camilla; Jakobsson, P. J. et al.

Ingår i Planta Medica, 2016.

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DOI för Circular disulfide-rich peptide scaffolds as anti-citrullinated peptide antibody inhibitors