Farmaceutisk Fysik

Single-particle fabric tensors for assemblies of spherical particles

Frenning, Göran

Ingår i Computer Methods in Applied Mechanics and Engineering, 2024

• DOI för Single-particle fabric tensors for assemblies of spherical particles
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Effective friction in adhesive mixtures intended for inhalation: Simulation of oblique impact of adhesive units

Sarangi, Sohan; Frenning, Göran

Ingår i Powder Technology, 2023

• DOI för Effective friction in adhesive mixtures intended for inhalation: Simulation of oblique impact of adhesive units
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A new modelling approach for dissolution of polydisperse powders

van der Zwaan, Ires; Frenning, Göran

Ingår i International Journal of Pharmaceutics, 2023

• DOI för A new modelling approach for dissolution of polydisperse powders
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A Voronoi strain-based method for granular materials and continua

Frenning, Göran

Ingår i Computational particle mechanics, s. 427-443, 2023

• DOI för A Voronoi strain-based method for granular materials and continua
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Segregation in inhalable powders: Quantification of the effect of vibration on adhesive mixtures

Sarangi, Sohan; Simonsson, Anna; Frenning, Göran

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 107-119, 2023

• DOI för Segregation in inhalable powders: Quantification of the effect of vibration on adhesive mixtures
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Engineered microparticles of hyaluronic acid hydrogel for controlled pulmonary release of salbutamol sulphate

Nikjoo, Dariush; van der Zwaan, Ires; Rudén, Jonas; Frenning, Göran

Ingår i International Journal of Pharmaceutics, 2023

• DOI för Engineered microparticles of hyaluronic acid hydrogel for controlled pulmonary release of salbutamol sulphate
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On the thermodynamic consistency of the Drucker-Prager Cap model: Modification of the plastic potential and analysis of unloading

Frenning, Göran

Ingår i Powder Technology, 2023

• DOI för On the thermodynamic consistency of the Drucker-Prager Cap model: Modification of the plastic potential and analysis of unloading
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Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran; Gråsjö, Johan

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 1-10, 2022

• DOI för Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness
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Towards a macroscopically consistent discrete method for granular materials: Delaunay strain-based formulation

Frenning, Göran

Ingår i COMPUTATIONAL PARTICLE MECHANICS, s. 1105-1118, 2022

• DOI för Towards a macroscopically consistent discrete method for granular materials: Delaunay strain-based formulation
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Characterization of Membrane-Type Dissolution Profiles of Clinically Available Orally Inhaled Products Using a Weibull Fit and a Mechanistic Model

van der Zwaan, Irès; Franek, Frans; Fransson, Rebecca; Tehler, Ulrika et al.

Ingår i Molecular Pharmaceutics, s. 3114-3124, 2022

• DOI för Characterization of Membrane-Type Dissolution Profiles of Clinically Available Orally Inhaled Products Using a Weibull Fit and a Mechanistic Model
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Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, 2022

• DOI för Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation
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On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, 2021

• DOI för On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients
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Effect of carrier size and mechanical properties on adhesive unit stability for inhalation: A numerical study

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Ingår i Powder Technology, s. 230-239, 2021

• DOI för Effect of carrier size and mechanical properties on adhesive unit stability for inhalation: A numerical study
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Effect of fine particle shape on the stability and performance of adhesive mixtures intended for inhalation

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Ingår i Powder Technology, s. 299-305, 2021

• DOI för Effect of fine particle shape on the stability and performance of adhesive mixtures intended for inhalation
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Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran

Ingår i Pharmaceutics, 2021

• DOI för Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities
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Hyaluronic Acid Hydrogels for Controlled Pulmonary Drug Delivery-A Particle Engineering Approach

Nikjoo, Dariush; van der Zwaan, Ires; Brülls, Mikael; Tehler, Ulrika et al.

Ingår i Pharmaceutics, 2021

• DOI för Hyaluronic Acid Hydrogels for Controlled Pulmonary Drug Delivery-A Particle Engineering Approach
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Nanoscale characterization of PEGylated phospholipid coatings formed by spray drying on silica microparticles

An, Junxue; Forchheimer, Daniel; Savmarker, Jonas; Brulls, Mikael et al.

Ingår i Journal of Colloid and Interface Science, s. 92-100, 2020

• DOI för Nanoscale characterization of PEGylated phospholipid coatings formed by spray drying on silica microparticles
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Numerical modeling of collision of adhesive units: Stability and mechanical properties during handling

Sarangi, Sohan; Thalberg, Kyrre; Frenning, Göran

Ingår i Chemical Engineering Science: X, 2020

• DOI för Numerical modeling of collision of adhesive units: Stability and mechanical properties during handling
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Model for the Analysis of Membrane-Type Dissolution Tests for Inhaled Drugs

Frenning, Göran; van der Zwaan, Ires; Franek, Frans; Fransson, Rebecca et al.

Ingår i Molecular Pharmaceutics, s. 2426-2434, 2020

• DOI för Model for the Analysis of Membrane-Type Dissolution Tests for Inhaled Drugs
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Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Jonsson, Henrik; Öhman-Mägi, Caroline; Alderborn, Göran; Isaksson, Per et al.

Ingår i International Journal of Pharmaceutics, s. 130-137, 2019

• DOI för Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Jonsson, Henrik; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 74-81, 2019

• DOI för Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, s. 148-160, 2019

• DOI för Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model
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Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Ingår i International Journal of Pharmaceutics, s. 143-156, 2018

• DOI för Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Nordström, Josefina; Alderborn, Göran; Frenning, Göran

Ingår i International Journal of Pharmaceutics, s. 120-131, 2018

• DOI för Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Peptide loaded microgels as antimicrobial surface coatings

Nyström, Lina; Nordström, Randi; Frenning, Göran; Saunders, Brian et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2017

Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions

Jonsson, Henrik; Gråsjö, Johan; Frenning, Göran

Ingår i Powder Technology, s. 347-355, 2017

• DOI för Mechanical behaviour of ideal elastic-plastic particles subjected to different triaxial loading conditions
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Computational fluid dynamics (CFD) studies of a miniaturized dissolution system

Frenning, Göran; Ahnfelt, Emelie; Sjögren, Erik; Lennernäs, Hans

Ingår i International Journal of Pharmaceutics, s. 274-281, 2017

• DOI för Computational fluid dynamics (CFD) studies of a miniaturized dissolution system
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Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Persson, Ann-Sofie; Nordström, Josefina; Frenning, Göran; Alderborn, Göran

Ingår i Chemical engineering research & design, s. 183-191, 2016

• DOI för Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Electrostatic Swelling Transitions in Surface-Bound Microgels

Nyström, Lina; Alvarez-Asencio, Ruben; Frenning, Göran; Saunders, Brian R. et al.

Ingår i ACS Applied Materials and Interfaces, s. 27129-27139, 2016

• DOI för Electrostatic Swelling Transitions in Surface-Bound Microgels

Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression

Jonsson, Henrik; Frenning, Göran

Ingår i Powder Technology, s. 79-87, 2016

• DOI för Investigations of single microcrystalline cellulose-based granules subjected to confined triaxial compression
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Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions

Frenning, Göran

Ingår i MethodsX, s. 79-90, 2015

• DOI för Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions
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An apparatus for confined triaxial testing of single particles

Jonsson, Henrik; Gråsjö, Johan; Nordström, Josefina; Johansson, Niklas et al.

Ingår i Powder Technology, s. 121-127, 2015

• DOI för An apparatus for confined triaxial testing of single particles
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Towards a mechanistic contact model for elastoplastic particles at high relative densities

Frenning, Göran

Ingår i Finite elements in analysis and design (Print), s. 56-60, 2015

• DOI för Towards a mechanistic contact model for elastoplastic particles at high relative densities
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An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model

Persson, Ann-Sofie; Frenning, Göran

Ingår i Powder Technology, s. 257-264, 2015

• DOI för An experimental evaluation of discrete element simulations of confined powder compression using an extended truncated-sphere model
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Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

Widenbring, Ronja; Frenning, Göran; Malmsten, Martin

Ingår i Biomacromolecules, s. 3671-3678, 2014

• DOI för Chain and Pore-Blocking Effects on Matrix Degradation in Protein-Loaded Microgels

Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

Mansson, Ronja; Frenning, Göran; Malmsten, Martin

Ingår i Biomacromolecules, s. 2317-2325, 2013

• DOI för Factors Affecting Enzymatic Degradation of Microgel-Bound Peptides

The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation

Persson, Ann-Sofie; Frenning, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 241-250, 2013

• DOI för The influence of rolling friction on the shear behaviour of non-cohesive pharmaceutical granules: An experimental and numerical investigation
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The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 3-12, 2013

• DOI för The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction
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Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis

Frenning, Göran

Ingår i Materials letters (General ed.), s. 365-368, 2013

• DOI för Towards a mechanistic model for the interaction between plastically deforming particles under confined conditions: A numerical and analytical analysis
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A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Mahmoodi, Foad; Klevan, Ingvild; Nordström, Josefina; Alderborn, Göran et al.

Ingår i International Journal of Pharmaceutics, s. 295-299, 2013

• DOI för A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter
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An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method

Persson, Ann-Sofie; Frenning, Göran

Ingår i Powder Technology, s. 249-256, 2012

• DOI för An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method
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An experimental evaluation of an effective medium based compaction equation

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 49-55, 2012

• DOI för An experimental evaluation of an effective medium based compaction equation
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A model describing the internal structure of core/shell hydrogels

Gernandt, Jonas; Frenning, Göran; Richtering, Walter; Hansson, Per

Ingår i Soft Matter, s. 10327-10338, 2011

• DOI för A model describing the internal structure of core/shell hydrogels

Modelling drug release from inert matrix systems: From moving-boundary to continuous-field descriptions

Frenning, Göran

Ingår i International Journal of Pharmaceutics, s. 88-99, 2011

• DOI för Modelling drug release from inert matrix systems: From moving-boundary to continuous-field descriptions
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The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis

Frenning, Göran; Gråsjö, Johan; Hansson, Per

Ingår i AIChE Journal, s. 1402-1408, 2011

• DOI för The Release of Catanionic Mixtures Embedded in Gels: An Approximate Analytical Analysis
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Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran

Ingår i European Journal of Pharmaceutical Sciences, s. 199-209, 2011

• DOI för Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study
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Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices

Jämstorp, Erik; Strømme, Maria; Frenning, Göran

Ingår i Journal of Pharmaceutical Sciences, s. 4338-4348, 2011

• DOI för Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices
• Ladda ner fulltext (pdf) av Modeling structure-function relationships for diffusive drug transport in inert porous geopolymer matrices

Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 283-290, 2011

• DOI för Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression
• Ladda ner fulltext (pdf) av Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Compression mechanics of granule beds: A combined finite/discrete element study

Frenning, Göran

Ingår i Chemical Engineering Science, s. 2464-2471, 2010

• DOI för Compression mechanics of granule beds: A combined finite/discrete element study
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Effect of lubrication on the distribution of force between spherical agglomerates during compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Ingår i Powder Technology, s. 69-74, 2010

• DOI för Effect of lubrication on the distribution of force between spherical agglomerates during compression
• Ladda ner fulltext (pdf) av Effect of lubrication on the distribution of force between spherical agglomerates during compression