Senaste publikationer

Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum

Zillich, Lea; Poisel, Eric; Frank, Josef; Foo, Jerome C. et al.

Ingår i Translational Psychiatry, 2022.

DOI för Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum Ladda ner fulltext (pdf) av Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022.

DOI för 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands Ladda ner fulltext (pdf) av 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Nandrolone decanoate and testosterone undecanoate differently affect stress hormones, neurotransmitter systems, and general activity in the male rat

Zelleroth, Sofia; Nylander, Erik; Kjellgren, Ellinor; Gröndbladh, Alfhild et al.

Ingår i Behavioural Brain Research, 2022.

DOI för Nandrolone decanoate and testosterone undecanoate differently affect stress hormones, neurotransmitter systems, and general activity in the male rat Ladda ner fulltext (pdf) av Nandrolone decanoate and testosterone undecanoate differently affect stress hormones, neurotransmitter systems, and general activity in the male rat

Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Stam, Frida; Lind, Sara Florén; Schroff, Anja; Zelleroth, Sofia et al.

Ingår i Current Issues in Molecular Biology, s. 5000-5012, 2022.

DOI för Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures Ladda ner fulltext (pdf) av Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Gopalan, Greeshma; Palo-Nieto, Carlos; Petersen, Nadia N.; Hallberg, Mathias et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022.

DOI för Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds Ladda ner fulltext (pdf) av Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders

Bakalkin, Georgy; Lukoyanov, Nikolay; Lavrov, Igor; Zhang, Mengliang

Ingår i Neural Regeneration Research, s. 2431-2433, 2022.

DOI för The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders Ladda ner fulltext (pdf) av The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders

The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

Ingår i European Journal of Pharmacology, 2021.

DOI för The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

The effects of morphine, methadone, and fentanyl on mitochondria: A live cell imaging study

Nylander, Erik; Zelleroth, Sofia; Nyberg, Fred; Gröndbladh, Alfhild et al.

Ingår i Brain Research Bulletin, s. 126-134, 2021.

DOI för The effects of morphine, methadone, and fentanyl on mitochondria: A live cell imaging study

Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

Lukoyanov, Nikolay; Watanabe, Hiroyuki; Carvalho, Liliana S.; Kononenko, Olga et al.

Ingår i eLIFE, 2021.

DOI för Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury Ladda ner fulltext (pdf) av Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring

Carvalho, Liliana S.; Brito, Helena M.; Lukoyanova, Elena A.; Maia, Gisela H. et al.

Ingår i European Journal of Neuroscience, s. 3621-3633, 2021.

DOI för Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring Ladda ner fulltext (pdf) av Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring

Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats

Bakalkin, Georgy; Nosova, Olga; Sarkisyan, Daniil; Hallberg, Mathias et al.

Ingår i Experimental Brain Research, s. 2221-2232, 2021.

DOI för Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats Ladda ner fulltext (pdf) av Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats

Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

Ingår i Journal of Neurotrauma, s. 1679-1688, 2021.

DOI för Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury

Watanabe, Hiroyuki; Kononenko, Olga; Sarkisyan, Daniil; Andersen, Marlene Storm et al.

Ingår i eNeuro, 2021.

DOI för Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury Ladda ner fulltext (pdf) av Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Jia, Tianye; Chu, Congying; Liu, Yun; van Dongen, Jenny et al.

Ingår i Molecular Psychiatry, s. 3884-3895, 2021.

DOI för Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group Ladda ner fulltext (pdf) av Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence

Meng, Weida; Sjoholm, Louise K.; Kononenko, Olga; Tay, Nicole et al.

Ingår i Molecular Psychiatry, s. 4367-4382, 2021.

DOI för Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence

Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury

Bakalkin, Georgy; Kahle, Anika; Sarkisyan, Daniil; Watanabe, Hiroyuki et al.

Ingår i European Journal of Neuroscience, s. 5560-5573, 2021.

DOI för Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury Ladda ner fulltext (pdf) av Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury

Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures

Zelleroth, Sofia; Nylander, Erik; Örtenblad, Axel; Stam, Frida et al.

Ingår i Journal of Steroid Biochemistry and Molecular Biology, 2021.

DOI för Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures Ladda ner fulltext (pdf) av Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures

Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

Ingår i Methods in Molecular Biology, s. 171-180, 2021.

DOI för Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

Nikulin, Sergey; Zakharova, Galina; Poloznikov, Andrey; Raigorodskaya, Maria et al.

Ingår i Frontiers in Genetics, 2021.

DOI för Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells Ladda ner fulltext (pdf) av Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2021.

DOI för N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

Ingår i European Journal of Pharmacology, 2020.

DOI för Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages Ladda ner fulltext (pdf) av Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

Ingår i Metabolomics, 2020.

DOI för Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver Ladda ner fulltext (pdf) av Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

Growth hormone increases dendritic spine density in primary hippocampal cell cultures

Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

Ingår i Growth Hormone & IGF Research, s. 42-47, 2020.

DOI för Growth hormone increases dendritic spine density in primary hippocampal cell cultures

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Ingår i ChemistryOpen, s. 325-337, 2020.

DOI för Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors Ladda ner fulltext (pdf) av Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

Ingår i RSC Medicinal chemistry, s. 234-244, 2020.

DOI för Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Growing knowledge: How growth hormone improves learning

Nyberg, Fred; Hallberg, Mathias

Ingår i Acta Physiologica, 2020.

DOI för Growing knowledge: How growth hormone improves learning

Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

Ingår i Biomolecules, 2020.

DOI för Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists Ladda ner fulltext (pdf) av Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Mpakali, Anastasia; Saridakis, Emmanuel; Giastas, Petros; Maben, Zachary et al.

Ingår i ACS Medicinal Chemistry Letters, s. 1429-1434, 2020.

DOI för Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Insulin-regulated aminopeptidase inhibitor-mediated increases in dendritic spine density are facilitated by glucose uptake

Seyer, Benjamin; Diwakarla, Shanti; Burns, Peta; Hallberg, Anders et al.

Ingår i Journal of Neurochemistry, s. 485-494, 2020.

DOI för Insulin-regulated aminopeptidase inhibitor-mediated increases in dendritic spine density are facilitated by glucose uptake

Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

Ingår i Brain Communications, 2020.

DOI för Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry Ladda ner fulltext (pdf) av Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

Watanabe, Hiroyuki; Nosova, Olga; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

Ingår i Brain Communications, 2020.

DOI för Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism Ladda ner fulltext (pdf) av Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

Correlations between sex-related hormones, alcohol dependence and alcohol craving

Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

Ingår i Drug And Alcohol Dependence, s. 183-190, 2019.

DOI för Correlations between sex-related hormones, alcohol dependence and alcohol craving Ladda ner fulltext (pdf) av Correlations between sex-related hormones, alcohol dependence and alcohol craving

Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

Ingår i American Journal of Psychiatry, s. 146-155, 2019.

DOI för Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

Ingår i Restorative Neurology and Neuroscience, s. 87-96, 2019.

DOI för Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord Ladda ner fulltext (pdf) av Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

Mueller, Christian P.; Chu, Congying; Qin, Liya; Liu, Chunyu et al.

Ingår i Cerebral Cortex, s. 1736-1751, 2019.

DOI för The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study Ladda ner fulltext (pdf) av The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

High affinity rigidified AT(2) receptor ligands with indane scaffolds

Wallinder, Charlotta; Sköld, Christian; Sundholm, Sara; Guimond, Marie-Odile et al.

Ingår i MedChemComm, s. 2146-2160, 2019.

DOI för High affinity rigidified AT(2) receptor ligands with indane scaffolds Ladda ner fulltext (pdf) av High affinity rigidified AT(2) receptor ligands with indane scaffolds

Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

Duarte, Joana; Fernandes, Elisabete C.; Kononenko, Olga; Sarkisyan, Daniil et al.

Ingår i Brain Research, s. 182-189, 2019.

DOI för Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

Ingår i Neuroscience, s. 172-183, 2019.

DOI för Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures Ladda ner fulltext (pdf) av Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Ingår i ChemistryOpen, s. 114-125, 2019.

DOI för A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode Ladda ner fulltext (pdf) av A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

Ingår i Translational Psychiatry, 2018.

DOI för Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics Ladda ner fulltext (pdf) av Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

Ingår i Molecular Neurobiology, s. 7049-7061, 2018.

DOI för Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics. Ladda ner fulltext (pdf) av Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

Kononenko, Olga; Mityakina, Irina; Galatenko, Vladimir; Watanabe, Hiroyuki et al.

Ingår i Brain Research, s. 78-83, 2018.

DOI för Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

ASYMMETRIC HINDLIMB POSTURE AND WITHDRAW REFLEXES INDUCED BY UNILATERAL BRAIN INJURY ARE ENCODED IN SPINAL CORD

Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Thelin, Jonas et al.

Ingår i Journal of Neurotrauma, s. A208-A208, 2018.

Asymmetric Hindlimb Motor Response To Focal Traumatic Brain Injury Is Controlled By Side-Specific Opioid Mechanism

Watanabe, Hiroyuki; Zhang, Mengliang; Sarkisyan, Daniil; Kononenko, Olga et al.

Ingår i Journal of Neurotrauma, s. A79-A79, 2018.

Contralesional Hindlimb Motor Response Induced By Unilateral Brain Injury: Evidence For Extra Spinal Mechanism

Lukoyanov, Nikolay; Carvalho, Liliana; Watanabe, Hiroyuki; Zhang, Mengliang et al.

Ingår i Journal of Neurotrauma, s. A201-A201, 2018.

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Wannberg, Johan; Isaksson, Rebecka; Bremberg, Ulf; Backlund, Maria et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 519-522, 2018.

DOI för A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

Reddy Vanga, Sudarsana; Sävmarker, Jonas; Ng, Leelee; Larhed, Mats et al.

Ingår i ACS Omega, s. 4509-4521, 2018.

DOI för Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides Ladda ner fulltext (pdf) av Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

Ahmed, Aisha S.; Gedin, Per; Hugo, Anders; Bakalkin, Georgy et al.

Ingår i Journal of Immunology, s. 1918-1927, 2018.

DOI för Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

Chronic administration of morphine using mini-osmotic pumps affects spatial memory in the male rat

Brolin, Erika; Zelleroth, Sofia; Jonsson, Anna; Hallberg, Mathias et al.

Ingår i Pharmacology, Biochemistry and Behavior, s. 1-8, 2018.

DOI för Chronic administration of morphine using mini-osmotic pumps affects spatial memory in the male rat

An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

Skogh, Anna; Lesniak, Anna; Sköld, Christian; Karlgren, Maria et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 2446-2450, 2018.

DOI för An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice