Senaste publikationer

Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum

Zillich, Lea; Poisel, Eric; Frank, Josef; Foo, Jerome C. et al.

Ingår i Translational Psychiatry, 2022.

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DOI för Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum Ladda ner fulltext (pdf) av Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum

The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders

Bakalkin, Georgy; Lukoyanov, Nikolay; Lavrov, Igor; Zhang, Mengliang

Ingår i Neural Regeneration Research, s. 2431-2433, 2022.

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DOI för The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders Ladda ner fulltext (pdf) av The left-right side-specific endocrine signaling: implications for neurological deficits in stroke and neurodevelopmental disorders

Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

Lukoyanov, Nikolay; Watanabe, Hiroyuki; Carvalho, Liliana S.; Kononenko, Olga et al.

Ingår i eLIFE, 2021.

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DOI för Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury Ladda ner fulltext (pdf) av Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring

Carvalho, Liliana S.; Brito, Helena M.; Lukoyanova, Elena A.; Maia, Gisela H. et al.

Ingår i European Journal of Neuroscience, s. 3621-3633, 2021.

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DOI för Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring Ladda ner fulltext (pdf) av Unilateral brain injury to pregnant rats induces asymmetric neurological deficits in the offspring

Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats

Bakalkin, Georgy; Nosova, Olga; Sarkisyan, Daniil; Hallberg, Mathias et al.

Ingår i Experimental Brain Research, s. 2221-2232, 2021.

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DOI för Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats Ladda ner fulltext (pdf) av Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats

Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

Ingår i Journal of Neurotrauma, s. 1679-1688, 2021.

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DOI för Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury

Watanabe, Hiroyuki; Kononenko, Olga; Sarkisyan, Daniil; Andersen, Marlene Storm et al.

Ingår i eNeuro, 2021.

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DOI för Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury Ladda ner fulltext (pdf) av Left-right side-specific neuropeptide mechanism mediates contralateral responses to a unilateral brain injury

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Jia, Tianye; Chu, Congying; Liu, Yun; van Dongen, Jenny et al.

Ingår i Molecular Psychiatry, s. 3884-3895, 2021.

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DOI för Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group Ladda ner fulltext (pdf) av Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence

Meng, Weida; Sjoholm, Louise K.; Kononenko, Olga; Tay, Nicole et al.

Ingår i Molecular Psychiatry, s. 4367-4382, 2021.

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DOI för Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence

Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury

Bakalkin, Georgy; Kahle, Anika; Sarkisyan, Daniil; Watanabe, Hiroyuki et al.

Ingår i European Journal of Neuroscience, s. 5560-5573, 2021.

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DOI för Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury Ladda ner fulltext (pdf) av Coordinated expression of the renin-angiotensin genes in the lumbar spinal cord: Lateralization and effects of unilateral brain injury

Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

Nikulin, Sergey; Zakharova, Galina; Poloznikov, Andrey; Raigorodskaya, Maria et al.

Ingår i Frontiers in Genetics, 2021.

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DOI för Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells Ladda ner fulltext (pdf) av Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

Ingår i Brain Communications, 2020.

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DOI för Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry Ladda ner fulltext (pdf) av Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

Watanabe, Hiroyuki; Nosova, Olga; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

Ingår i Brain Communications, 2020.

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DOI för Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism Ladda ner fulltext (pdf) av Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

Correlations between sex-related hormones, alcohol dependence and alcohol craving

Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

Ingår i Drug And Alcohol Dependence, s. 183-190, 2019.

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DOI för Correlations between sex-related hormones, alcohol dependence and alcohol craving Ladda ner fulltext (pdf) av Correlations between sex-related hormones, alcohol dependence and alcohol craving

Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

Ingår i American Journal of Psychiatry, s. 146-155, 2019.

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DOI för Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

Ingår i Restorative Neurology and Neuroscience, s. 87-96, 2019.

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DOI för Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord Ladda ner fulltext (pdf) av Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

Mueller, Christian P.; Chu, Congying; Qin, Liya; Liu, Chunyu et al.

Ingår i Cerebral Cortex, s. 1736-1751, 2019.

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DOI för The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study Ladda ner fulltext (pdf) av The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

Duarte, Joana; Fernandes, Elisabete C.; Kononenko, Olga; Sarkisyan, Daniil et al.

Ingår i Brain Research, s. 182-189, 2019.

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DOI för Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

Ingår i Translational Psychiatry, 2018.

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DOI för Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics Ladda ner fulltext (pdf) av Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

Ingår i Molecular Neurobiology, s. 7049-7061, 2018.

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DOI för Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics. Ladda ner fulltext (pdf) av Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

Kononenko, Olga; Mityakina, Irina; Galatenko, Vladimir; Watanabe, Hiroyuki et al.

Ingår i Brain Research, s. 78-83, 2018.

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DOI för Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

ASYMMETRIC HINDLIMB POSTURE AND WITHDRAW REFLEXES INDUCED BY UNILATERAL BRAIN INJURY ARE ENCODED IN SPINAL CORD

Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Thelin, Jonas et al.

Ingår i Journal of Neurotrauma, s. A208-A208, 2018.

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Asymmetric Hindlimb Motor Response To Focal Traumatic Brain Injury Is Controlled By Side-Specific Opioid Mechanism

Watanabe, Hiroyuki; Zhang, Mengliang; Sarkisyan, Daniil; Kononenko, Olga et al.

Ingår i Journal of Neurotrauma, s. A79-A79, 2018.

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Contralesional Hindlimb Motor Response Induced By Unilateral Brain Injury: Evidence For Extra Spinal Mechanism

Lukoyanov, Nikolay; Carvalho, Liliana; Watanabe, Hiroyuki; Zhang, Mengliang et al.

Ingår i Journal of Neurotrauma, s. A201-A201, 2018.

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Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

Ahmed, Aisha S.; Gedin, Per; Hugo, Anders; Bakalkin, Georgy et al.

Ingår i Journal of Immunology, s. 1918-1927, 2018.

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DOI för Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

Ingår i Cerebral Cortex, s. 3129-3142, 2018.

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DOI för Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

Ruggeri, Barbara; Macare, Christine; Stopponi, Serena; Jia, Tianye et al.

Ingår i Journal of Child Psychology and Psychiatry and Allied Disciplines, s. 50-658, 2018.

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DOI för Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Kononenko, Olga; Bazov, Igor; Watanabe, Hiroyuki; Gerashchenko, Ganna et al.

Ingår i Biochimica et Biophysica Acta, s. 246-255, 2017.

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DOI för Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation

Sarkisyan, Daniil; Bazov, Igor; Watanabe, Hiroyuki; Kononenko, Olga et al.

Ingår i Acta Neuropathologica, s. 485-487, 2017.

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DOI för Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation

Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis.

Ahmed, Aisha Siddiqah; Ahmed, Mahmood; Li, Jian; Gu, Harvest F et al.

Ingår i International journal of rheumatic diseases, s. 25-32, 2017.

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DOI för Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis.

Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry

Bivehed, Erik; Strömvall, Robert; Bergquist, Jonas; Bakalkin, Georgy et al.

Ingår i Peptides, s. 20-27, 2017.

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DOI för Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry Ladda ner fulltext (pdf) av Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry

Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies

Sui, Ping; Watanabe, Hiroyuki; Artemenko, Konstantin; Sun, Wei et al.

Ingår i European journal of mass spectrometry, s. 105-115, 2017.

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DOI för Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies

Intra- and interregional coregulation of opioid genes: broken symmetry in spinal circuits

Kononenko, Olga; Galatenko, Vladimir; Andersson, Malin; Bazov, Igor et al.

Ingår i The FASEB Journal, s. 1953-1963, 2017.

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DOI för Intra- and interregional coregulation of opioid genes: broken symmetry in spinal circuits

Lateralized response in endogenous pathogenic peptides dynorphins caused by traumatic brain injury: Relevance for human psychopathology

Yakovleva, Tatjana; Watanabe, Hiroyuki; Bakalkin, Georgy

Ingår i Brain Injury, s. 733-733, 2016.

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TBI induced spinal cord plasticity: The endogenous opioid system mediates trauma effects on motor reflexes

Bakalkin, Georgy; Watanabe, Hiroyuki; Kononenko, Olga; Stålhandske, Lada et al.

Ingår i Brain Injury, s. 712-712, 2016.

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Altered secondary structure of Dynorphin A associates with loss of opioid signalling and NMDA-mediated excitotoxicity in SCA23

Smeets, Cleo J. L. M.; Zmorzynska, Justyna; Melo, Manuel N.; Stargardt, Anita et al.

Ingår i Human Molecular Genetics, s. 2728-2737, 2016.

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DOI för Altered secondary structure of Dynorphin A associates with loss of opioid signalling and NMDA-mediated excitotoxicity in SCA23

The dynorphin/kappa-opioid receptor system: molecular and epigenetic adaptations in emotional circuitry of alcoholics

Bakalkin, Georgy; Yakovleva, Tatiana

Ingår i European Neuropsychopharmacology, s. S152-S152, 2016.

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KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, Gunter; Liu, Chunyu; O'Reilly, Paul; Gao, He et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 14372-14377, 2016.

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DOI för KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference

Sex-Specific Association of Prodynorphin Sequence Variation with Alcohol Dependence and Related Phenotypes

Winham, Stacey J.; Preuss, Ulrich W.; Geske, Jennifer R.; Zill, Peter et al.

Ingår i Biological Psychiatry, s. 408S-408S, 2015.

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Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction

Maximyuk, O.; Khmyz, V.; Lindskog, C-J; Vukojevic, V. et al.

Ingår i Cell Death and Disease, 2015.

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DOI för Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction Ladda ner fulltext (pdf) av Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction

Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis

Ruggeri, Barbara; Nymberg, Charlotte; Vuoksimaa, Eero; Lourdusamy, Anbarasu et al.

Ingår i American Journal of Psychiatry, s. 543-552, 2015.

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DOI för Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis

EPIGENOME IN THE BRAIN OF HUMAN ALCOHOLICS: GENETICALLY-REGULATED TRAJECTORIES OF DNA METHYLATION

Sarkisyan, Daniil; Bazov, Igor; Yakovleva, Tatiana; Bakalkin, Georgy

Ingår i Alcohol and Alcoholism, 2015.

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Gender Effects on Association Between PDYN Sequence Variation with Alcohol Dependence and Related Phenotypes

Karpyak, V. M.; Winham, S. J.; Biernacka, J. M.; Geske, J. et al.

Ingår i Alcohol and Alcoholism, 2015.

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THE ENDOGENOUS OPIOID SYSTEM: DYSREGULATION IN THE STRIATUM OF HUMAN ALCOHOLICS

Bazov, Igor; Sarkisyan, Daniil; Hussain, M. Z.; Watanabe, Hiroyuki et al.

Ingår i Alcohol and Alcoholism, 2015.

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OPIOIDERGIC MECHANISM IN ALCOHOLISM: TRANSLATIONAL STUDIES IN RODENTS AND HUMANS

Hirth, N.; Sommer, W. H.; Bakalkin, Georgy; Spanagel, R. et al.

Ingår i Alcohol and Alcoholism, 2015.

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Molecular mechanism for opioid dichotomy: bidirectional effect of mu-opioid receptors on P2X(3) receptor currents in rat sensory neurones

Chizhmakov, Igor; Kulyk, Vyacheslav; Khasabova, Iryna; Khasabov, Sergey et al.

Ingår i Purinergic Signalling Purinergic Signalling, s. 171-181, 2015.

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DOI för Molecular mechanism for opioid dichotomy: bidirectional effect of mu-opioid receptors on P2X(3) receptor currents in rat sensory neurones

Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain

Watanabe, Hiroyuki; Fitting, Sylvia; Hussain, Muhammad; Kononenko, Olga et al.

Ingår i Cerebral Cortex, s. 97-108, 2015.

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DOI för Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain Ladda ner fulltext (pdf) av Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain

Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23

Smeets, Cleo J. L. M.; Jezierska, Justyna; Watanabe, Hiroyuki; Duarri, Anna et al.

Ingår i Brain, s. 2537-2552, 2015.

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DOI för Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23

Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

Winham, Stacey J.; Preuss, Ulrich W.; Geske, Jennifer R.; Zill, Peter et al.

Ingår i Scientific Reports, 2015.

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DOI för Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent Ladda ner fulltext (pdf) av Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

Sarkisyan, Daniil; Hussain, Muhammad Zubair; Watanabe, Hiroyuki; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, 2015.

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DOI för Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics Ladda ner fulltext (pdf) av Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

Proteomics of Neuropathic Pain: Proteins and Signaling Pathways Affected in a Rat Model

Sui, Ping; Watanabe, Hiroyuki; Ossipov, Michael; Bakalkin, Georgy et al.

Ingår i Journal of Proteome Research, s. 3957-3965, 2014.

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DOI för Proteomics of Neuropathic Pain: Proteins and Signaling Pathways Affected in a Rat Model

Brain Area-Specific Dysregulation Of The Dynorphin/Kappa-Opioid Receptor System In Human Alcoholics: Implications For Pathogenesis

Bakalkin, Georgy; Yakovleva, Tatiana; Bazov, Igor

Ingår i Alcoholism, s. 345A-345A, 2014.

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Pdyn Rs2281285 Variat Is Associated With The Length Of Sobriety In Alcohol Dependent Subjects

Karpyak, V. M.; Preuss, U. W.; Geske, J.; Winham, S. J. et al.

Ingår i Alcoholism, s. 148A-148A, 2014.

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Variations in PDYN Sequence are Associated with Post-treatment Relapse in Alcohol Dependent Subjects

Karpyak, Victor M.; Winham, Stacey J.; Biernacka, Joanna M.; Geske, Jennifer et al.

Ingår i Biological Psychiatry, s. 352S-352S, 2014.

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Opioid neuropeptides make pores in plasma membrane: possible mechanism of signal transduction

Krishtal, O.; Maximyuk, O.; Khmyz, V.; Lindskog, C. et al.

Ingår i Acta Physiologica, s. 12-12, 2014.

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The left-right neurohormonal regulation in the brain: Lateralized endogenous opioid system

Bakalkin, Georgy

Ingår i Acta Physiologica, s. 12-12, 2014.

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PDYN, a gene implicated in brain/mental disorders, is targeted by REST in the adult human brain

Henriksson, Richard; Backman, Cristina M; Harvey, Brandon K; Kadyrova, Helena et al.

Ingår i Biochimica et Biophysica Acta, s. 1226-1232, 2014.

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DOI för PDYN, a gene implicated in brain/mental disorders, is targeted by REST in the adult human brain

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

Jin, Zhe; Bhandage, Amol K.; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, s. 288-, 2014.

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DOI för Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

Jin, Zhe; Bhandage, Amol K; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, s. 11-, 2014.

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DOI för Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

Bhandage, Amol K.; Jin, Zhe; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, 2014.

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DOI för GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

PDYN rs2281285 variant is associated with alcohol dependence in male but not female subjects

Karpyak, V. M.; Winham, S. J.; Preuss, U. W.; Zill, P. et al.

Ingår i European psychiatry, s. 1344-, 2013.

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DOI för PDYN rs2281285 variant is associated with alcohol dependence in male but not female subjects

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

Kuzmin, A.; Chefer, V.; Bazov, Igor; Meis, J. et al.

Ingår i Translational Psychiatry, s. e310-, 2013.

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DOI för Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

Dimethyl-Labeling-Based Protein Quantification and Pathway Search: A Novel Method of Spinal Cord Analysis Applicable for Neurological Studies

Sui, Ping; Watanabe, Hiroyuki; Ossipov, Michael H.; Porreca, Frank et al.

Ingår i Journal of Proteome Research, s. 2245-2252, 2013.

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DOI för Dimethyl-Labeling-Based Protein Quantification and Pathway Search: A Novel Method of Spinal Cord Analysis Applicable for Neurological Studies

Identification and characterization of novel PDYN mutations in dominant cerebellar ataxia cases.

Jezierska, Justyna; Stevanin, Giovanni; Watanabe, Hiroyuki; Fokkens, Michiel R et al.

Ingår i Journal of Neurology, s. 1807-1812, 2013.

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DOI för Identification and characterization of novel PDYN mutations in dominant cerebellar ataxia cases.

Minor Allele Of Pdyn Rs2281285 Snp Is Positively Associated With Drinking To Overcome Mental Or Somatic Problems

Preuss, U. W.; Winham, S. J.; Biernacka, J. M.; Cunningham, J. M. et al.

Ingår i Alcoholism, s. 66A-66A, 2013.

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The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction

Bazov, Igor; Kononenko, Olga; Watanabe, Hiroyuki; Kuntić, Vesna et al.

Ingår i Addiction Biology, s. 161-169, 2013.

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DOI för The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

Karpyak, Victor M; Winham, Stacey J; Preuss, Ulrich W; Zill, Peter et al.

Ingår i International Journal of Neuropsychopharmacology, s. 975-985, 2013.

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DOI för Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states Ladda ner fulltext (pdf) av Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

Dysregulation of the endogenous opioid system in the brain of human alcoholics

Bakalkin, Georgy; Bazov, Igor; Hussain, Muhammad Zubair; Sarkisyan, Daniil et al.

Ingår i European psychiatry, s. 2297-, 2013.

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DOI för Dysregulation of the endogenous opioid system in the brain of human alcoholics

PDYN rs2281285 Variant Association with Drinking to Avoid Emotional or Somatic Discomfort

Preuss, Ulrich W.; Winham, Stacey J.; Biernacka, Joanna M.; Geske, Jennifer R. et al.

Ingår i PLOS ONE, s. e78688-, 2013.

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DOI för PDYN rs2281285 Variant Association with Drinking to Avoid Emotional or Somatic Discomfort Ladda ner fulltext (pdf) av PDYN rs2281285 Variant Association with Drinking to Avoid Emotional or Somatic Discomfort

Dysregulation of the dynorphin/kappa-opioid receptor system in cortical areas of human alcoholics: shift in epigenetic mechanisms

Bakalkin, Georgy; Yakovleva, Tatiana

Ingår i Alcoholism, s. 357A-357A, 2012.

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Variations in PDYN sequence are associated with negative craving in alcohol dependent subjects

Karpyak, V.; Winham, S.; Biernacka, J.; Cunningham, J. et al.

Ingår i European psychiatry, 2012.

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DOI för Variations in PDYN sequence are associated with negative craving in alcohol dependent subjects

Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence

Walker, Brendan M.; Valdez, Glenn R.; McLaughlin, Jay P.; Bakalkin, Georgy

Ingår i Alcohol, s. 359-370, 2012.

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DOI för Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence

Lateralized Response of Dynorphin A Peptide Levels after Traumatic Brain Injury

Hussain, Zubair Muhammad; Fitting, Sylvia; Watanabe, Hiroyuki; Usynin, Ivan et al.

Ingår i Journal of Neurotrauma, s. 1785-1793, 2012.

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DOI för Lateralized Response of Dynorphin A Peptide Levels after Traumatic Brain Injury

Non-opioid nociceptive activity of human dynorphin mutants that cause neurodegenerative disorder spinocerebellar ataxia type 23

Watanabe, Hiroyuki; Mizoguchi, Hirokazu; Verbeek, Dineke S.; Kuzmin, Alexander et al.

Ingår i Peptides, s. 306-310, 2012.

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DOI för Non-opioid nociceptive activity of human dynorphin mutants that cause neurodegenerative disorder spinocerebellar ataxia type 23

Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis

Ahmed, Aisha S; Li, Jian; Erlandsson-Harris, Helena; Stark, André et al.

Ingår i Pain, s. 18-26, 2012.

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DOI för Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis

Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system

Sirohi, Sunil; Bakalkin, Georgy; Walker, Brendan M

Ingår i Frontiers in Molecular Neuroscience, s. 1-12, 2012.

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DOI för Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system

Repeated moderate-dose ethanol bouts impair cognitive function in Wistar rats

Kuzmin, Alexander; Liljequist, Sture; Meis, Jennifer; Chefer, Vladimir et al.

Ingår i Addiction Biology, s. 132-140, 2012.

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DOI för Repeated moderate-dose ethanol bouts impair cognitive function in Wistar rats

Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences

Taqi, Malik Mumtaz; Wärmländer, Sebastian K. T. S.; Yamskova, Olga; Madani, Fatemeh et al.

Ingår i PLOS ONE, s. e39605-, 2012.

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DOI för Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences Ladda ner fulltext (pdf) av Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

Jin, Zhe; Bazov, Igor; Kononenko, Olga; Korpi, Esa R et al.

Ingår i Frontiers in Cellular Neuroscience, 2012.

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DOI för Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics Ladda ner fulltext (pdf) av Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

Effects of the Circadian Rhythm Gene Period 1 (Per1) on Psychosocial Stress-Induced Alcohol Drinking

Dong, Li; Bilbao, Ainhoa; Laucht, Manfred; Henriksson, Richard et al.

Ingår i American Journal of Psychiatry, s. 1090-1098, 2011.

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DOI för Effects of the Circadian Rhythm Gene Period 1 (Per1) on Psychosocial Stress-Induced Alcohol Drinking

Repeated exposure to moderate doses of ethanol augments hippocampal glutamate neurotransmission by increasing release

Chefer, Vladimir; Meis, Jennifer; Wang, Grace; Kuzmin, Alexander et al.

Ingår i Addiction Biology, s. 229-237, 2011.

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DOI för Repeated exposure to moderate doses of ethanol augments hippocampal glutamate neurotransmission by increasing release

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Schumann, Gunter; Coin, Lachlan J.; Lourdusamy, Anbarasu; Charoen, Pimphen et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 7119-7124, 2011.

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DOI för Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Fluorescence imaging with single-molecule sensitivity and fluorescence correlation spectroscopy of cell-penetrating neuropeptides

Vukojević, Vladana; Gräslund, Astrid; Bakalkin, Georgy

Ingår i Neuropeptides, s. 147-170, 2011.

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DOI för Fluorescence imaging with single-molecule sensitivity and fluorescence correlation spectroscopy of cell-penetrating neuropeptides

Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics

Taqi, Malik Mumtaz; Bazov, Igor; Watanabe, Hiroyuki; Sheedy, Donna et al.

Ingår i Addiction Biology, s. 499-509, 2011.

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DOI för Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics

Perturbations of model membranes induced by pathogenic dynorphin A mutants causing neurodegeneration in human brain

Madani, Fatemeh; Taqi, Malik Mumtaz; Warmlander, Sebastian K. T. S.; Verbeek, Dineke S. et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 111-114, 2011.

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DOI för Perturbations of model membranes induced by pathogenic dynorphin A mutants causing neurodegeneration in human brain

Prodynorphin promoter SNP associated with alcohol dependence forms noncanonical AP-1 binding site that may influence gene expression in human brain

Taqi, Malik Mumtaz; Bazov, Igor; Watanabe, Hiroyuki; Nyberg, Fred et al.

Ingår i Brain Research, s. 18-25, 2011.

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DOI för Prodynorphin promoter SNP associated with alcohol dependence forms noncanonical AP-1 binding site that may influence gene expression in human brain

Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

Bakalkin, Georgy; Watanabe, Hiroyuki; Jezierska, Justyna; Depoorter, Cloë et al.

Ingår i American Journal of Human Genetics, s. 593-603, 2010.

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DOI för Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

Attenuation of Pain and Inflammation in Adjuvant-Induced Arthritis by the Proteasome Inhibitor MG132

Ahmed, Aisha S.; Li, Jian; Ahmed, Mahmood; Hua, Long et al.

Ingår i Arthritis and Rheumatism, s. 2160-2169, 2010.

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DOI för Attenuation of Pain and Inflammation in Adjuvant-Induced Arthritis by the Proteasome Inhibitor MG132

FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics

Watanabe, Hiroyuki; Henriksson, Richard; Ohnishi, Yoshinori N.; Ohnishi, Yoko H. et al.

Ingår i Addiction Biology, s. 294-297, 2009.

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DOI för FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics Ladda ner fulltext (pdf) av FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics

Expression of pronociceptin and its receptor is downregulated in the brain of human alcoholics

Kuzmin, Alexander; Bazov, Igor; Sheedy, Donna; Garrick, Therese et al.

Ingår i Brain Research, s. S80-85, 2009.

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DOI för Expression of pronociceptin and its receptor is downregulated in the brain of human alcoholics

Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine

Tan-No, Koichi; Shimoda, Masakazu; Watanabe, Kenya; Nakagawasai, Osamu et al.

Ingår i Neuroscience Letters, s. 365-368, 2009.

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DOI för Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine

Dysregulation of cell death machinery in the prefrontal cortex of human alcoholics

Johansson, Sofia; Ekström, Tomas J.; Marinova, Zoya; Ökvist, Anna et al.

Ingår i International Journal of Neuropsychopharmacology, s. 109-115, 2009.

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DOI för Dysregulation of cell death machinery in the prefrontal cortex of human alcoholics Ladda ner fulltext (pdf) av Dysregulation of cell death machinery in the prefrontal cortex of human alcoholics

Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics

Henriksson, Richard; Kuzmin, Alexander; Ökvist, Anna; Harper, Clive et al.

Ingår i Synapse, s. 829-33, 2008.

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DOI för Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

El-Hage, Nazira; Bruce-Keller, Annadora J; Yakovleva, Tatiana; Bazov, Igor et al.

Ingår i PLOS ONE, s. e4093-, 2008.

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DOI för Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides

Hugonin, Loïc; Vukojević, Vladana; Bakalkin, Georgy; Gräslund, Astrid

Ingår i Biochimica et Biophysica Acta - Biomembranes, s. 1267-1273, 2008.

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DOI för Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides

Control of chronic pain by the ubiquitin-proteasome system in the spinal cord

Ossipov, Michael H.; Bazov, Igor; Gardell, Luis R.; Kowal, Justin et al.

Ingår i Journal of Neuroscience, s. 8226-37, 2007.

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DOI för Control of chronic pain by the ubiquitin-proteasome system in the spinal cord Ladda ner fulltext (pdf) av Control of chronic pain by the ubiquitin-proteasome system in the spinal cord

Neuroadaptations in human chronic alcoholics: dysregulation of the NF-κB system

Ökvist, Anna; Johansson, Sofia; Kuzmin, Alexander; Bazov, Igor et al.

Ingår i PLoS ONE, s. e930-, 2007.

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DOI för Neuroadaptations in human chronic alcoholics: dysregulation of the NF-κB system Ladda ner fulltext (pdf) av Neuroadaptations in human chronic alcoholics: dysregulation of the NF-κB system

Validation of endogenous controls for quantitative gene expression analysis: Application on brain cortices of human chronic alcoholics

Johansson, Sofia; Fuchs, Andrea; Ökvist, Anna; Karimi, Mohsen et al.

Ingår i Brain Research, s. 20-8, 2007.

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DOI för Validation of endogenous controls for quantitative gene expression analysis: Application on brain cortices of human chronic alcoholics

Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons

Adjan, V. V.; Hauser, K. F.; Bakalkin, Georgy; Yakovleva, T. et al.

Ingår i Neuroscience, s. 724-36, 2007.

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DOI för Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons

The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking

Kuzmin, Alexander; Kreek, Mary Jeanne; Bakalkin, Georgy; Liljequist, Sture

Ingår i Neuropsychopharmacology, s. 902-10, 2007.

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DOI för The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking